PYRAZOLOPYRIDINES AND ANALOGS THEREOF

PYRAZOLOPYRIDINES AND ANALOGS THEREOF

Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, fo...

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Hauptverfasser: BONK, JASON D, KAVANAGH, MAUREEN A, MOSEMAN, JOAN T, HAYS, DAVID S, NIWAS, SHRI, KSHIRSAGAR, TUSHAR A, MOSER, WILLIAM H, DANIELSON, MICHAEL E, PRINCE, RYAN B, RADMER, MATTHEW R, HEPPNER, PHILIP D, GERSTER, JOHN F, STRONG, SARAH A
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Pyrazolopyridin-4-amines, pyrazoloquinolin-4-amines, pyrazolonaphthyridin-4-amines, 6,7,8,9-tetrahydropyrazoloquinolin-4-amines, and prodrugs thereof, pharmaceutical compositions containing the compounds, intermediates, methods of making, and methods of use of these compounds as immunomodulators, for inducing or inhibiting cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.