AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE

The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwa...

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Hauptverfasser: LIU, GANG, PARAS, NICK A, SMITH, ADRIAN LEONARD, DEMORIN, FRENEL FILS, BRENNAN, PAUL EDWARD, RETZ, DANIEL MARTIN
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creator LIU, GANG
PARAS, NICK A
SMITH, ADRIAN LEONARD
DEMORIN, FRENEL FILS
BRENNAN, PAUL EDWARD
RETZ, DANIEL MARTIN
description The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE
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