METHODS AND COMPOSITIONS FOR DEPLETING MITOCHONDRIAL DNA

The invention relates generally to compositions and methods for depleting mitochondrial DNA from cells. The invention further relates to animal models for mitochondrial DNA depletion for the study of various syndromes or diseases that affect mitochondria and mitochondrial DNA.

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Bibliographische Detailangaben
Hauptverfasser: PARE, JUSTIN M, SAFFRAN, HOLLY A, SMILEY, JAMES R, CORCORAN, JENNIFER A
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The invention relates generally to compositions and methods for depleting mitochondrial DNA from cells. The invention further relates to animal models for mitochondrial DNA depletion for the study of various syndromes or diseases that affect mitochondria and mitochondrial DNA.