METHOD FOR THE PREPARATION OF 2'-DEOXY-2',2'-DIFLUOROCYTIDINE

This invention relates to an improved method for stereoselectively preparing 2¢~-deoxy-2¢~,2¢~-difluorocytidine of formula (I), which comprises the steps of reacting a 1-halo ribofuranose compound of formula (III) with a nucleobase of formula (IV) in a solvent to obtain a nucleoside of formula (II)...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	PARK, GHA SEUNG, LEE, JAE CHUL, KIM, CHEOL KYONG, BANG, HYO-JEONG, LEE, JAEHEON, KIM, HAN KYONG, CHANG, YOUNG-KIL, LEE, GWAN SUN, LEE, MOONSUB, CHOI, CHANG-JU, LEE, HOE CHUL
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS
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