BIOCATALYTIC MANUFACTURING OF (METH)ACRYLYLCHOLINE OR 2-(N,N-DIMETHYLAMINO)ETHYL (METH)ACRYLATE

BIOCATALYTIC MANUFACTURING OF (METH)ACRYLYLCHOLINE OR 2-(N,N-DIMETHYLAMINO)ETHYL (METH)ACRYLATE

A biocatalytic method for the synthesis of 2-(N,N-dimethylamino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid, namely a method or process for the manufacture of acrylylcholine and/or methacrylylcholine, comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acry...

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Hauptverfasser: SYMES, KENNETH CHARLES, HUGHES, JONATHAN
Format: Patent
Sprache:eng ; fre
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BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
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creator SYMES, KENNETH CHARLES
HUGHES, JONATHAN
description A biocatalytic method for the synthesis of 2-(N,N-dimethylamino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid, namely a method or process for the manufacture of acrylylcholine and/or methacrylylcholine, comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acrylyl-CoA and/or methacrylyl-CoA in the presence of a biocatalyst with choline acetyltransferase activity, where preferably the acrylyl-CoA and/or methacrylyl-CoA is formed by reaction of acrylate and/or methacrylate with coenzyme A in the presence of an energy providing substance and a biocatalyst with S-acetyl coenzyme A synthetase activity (acetyl CoA synthetase activity); to (especially transformed, that is genetically modified) organisms having choline acetyltransferase activity and preferably in addition the acetyl CoA synthetase activity and their use in said process or method; the use of a biocatalyst with choline actyltransferase activity to carry out the transfer of the (meth)acrylyl moiety from (meth)acrylyl CoA to 2-(N,N-dimethylamino)ethanol and/or choline, in order to manufacture 2-(N,N-dimethylamino)ethyl(meth)acrylate and/or (meth)acrylylcholine; and further uses, organisms, processes and methods as described in the specification.
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to (especially transformed, that is genetically modified) organisms having choline acetyltransferase activity and preferably in addition the acetyl CoA synthetase activity and their use in said process or method; the use of a biocatalyst with choline actyltransferase activity to carry out the transfer of the (meth)acrylyl moiety from (meth)acrylyl CoA to 2-(N,N-dimethylamino)ethanol and/or choline, in order to manufacture 2-(N,N-dimethylamino)ethyl(meth)acrylate and/or (meth)acrylylcholine; and further uses, organisms, processes and methods as described in the specification.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2013</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130702&amp;DB=EPODOC&amp;CC=CA&amp;NR=2558189C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20130702&amp;DB=EPODOC&amp;CC=CA&amp;NR=2558189C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SYMES, KENNETH CHARLES</creatorcontrib><creatorcontrib>HUGHES, JONATHAN</creatorcontrib><title>BIOCATALYTIC MANUFACTURING OF (METH)ACRYLYLCHOLINE OR 2-(N,N-DIMETHYLAMINO)ETHYL (METH)ACRYLATE</title><description>A biocatalytic method for the synthesis of 2-(N,N-dimethylamino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid, namely a method or process for the manufacture of acrylylcholine and/or methacrylylcholine, comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acrylyl-CoA and/or methacrylyl-CoA in the presence of a biocatalyst with choline acetyltransferase activity, where preferably the acrylyl-CoA and/or methacrylyl-CoA is formed by reaction of acrylate and/or methacrylate with coenzyme A in the presence of an energy providing substance and a biocatalyst with S-acetyl coenzyme A synthetase activity (acetyl CoA synthetase activity); 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HUGHES, JONATHAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2558189C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2013</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>SYMES, KENNETH CHARLES</creatorcontrib><creatorcontrib>HUGHES, JONATHAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SYMES, KENNETH CHARLES</au><au>HUGHES, JONATHAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>BIOCATALYTIC MANUFACTURING OF (METH)ACRYLYLCHOLINE OR 2-(N,N-DIMETHYLAMINO)ETHYL (METH)ACRYLATE</title><date>2013-07-02</date><risdate>2013</risdate><abstract>A biocatalytic method for the synthesis of 2-(N,N-dimethylamino)ethanol and/or choline esters of acrylic acid and/or methacrylic acid, namely a method or process for the manufacture of acrylylcholine and/or methacrylylcholine, comprising reacting 2-(N,N-dimethylamino)ethanol and/or choline with acrylyl-CoA and/or methacrylyl-CoA in the presence of a biocatalyst with choline acetyltransferase activity, where preferably the acrylyl-CoA and/or methacrylyl-CoA is formed by reaction of acrylate and/or methacrylate with coenzyme A in the presence of an energy providing substance and a biocatalyst with S-acetyl coenzyme A synthetase activity (acetyl CoA synthetase activity); to (especially transformed, that is genetically modified) organisms having choline acetyltransferase activity and preferably in addition the acetyl CoA synthetase activity and their use in said process or method; the use of a biocatalyst with choline actyltransferase activity to carry out the transfer of the (meth)acrylyl moiety from (meth)acrylyl CoA to 2-(N,N-dimethylamino)ethanol and/or choline, in order to manufacture 2-(N,N-dimethylamino)ethyl(meth)acrylate and/or (meth)acrylylcholine; and further uses, organisms, processes and methods as described in the specification.</abstract><oa>free_for_read</oa></addata></record>
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
SPIRITS
VINEGAR
WINE
title BIOCATALYTIC MANUFACTURING OF (METH)ACRYLYLCHOLINE OR 2-(N,N-DIMETHYLAMINO)ETHYL (METH)ACRYLATE
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