HIV INTEGRASE INHIBITORS

Hydroxy (tetra- or hexa-)hydronaphthyridine dione compounds of Formula I are inhibitors of HIV integrase and inhibitors of HIV replication: (I) wherein a, R1?, R2?, R3?, R4? and R5? are defined herein. The compounds are useful in the prevention and treatment of infection by HIV and in the prevention...

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Hauptverfasser:	HAN, WEI, PAYNE, LINDA S, EGBERTSON, MELISSA, PYE, PHILIP J, FOSTER, BRUCE S, ASKIN, DAVID, WILLIAMS, PETER D, RUZEK, ROWENA D, ZHUANG, LINGHANG, OBLIGADO, VANESSA E, KIM, BOYOUNG, MORRISSETTE, MATTHEW M, ANGELAUD, REMY, CAMERON, MARK, ISAACS, RICHARD C. A, PERLOW, DEBRA S, NEILSON, LOU ANNE, HOERRNER, R. SCOTT, WAI, JOHN S, DOLLING, ULF H, MANCHENO, DANNY E
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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