METHOD OF ANTIGEN INCORPORATION INTO NEISSERIA BACTERIAL OUTER MEMBRANE VESICLES AND RESULTING VACCINE FORMULATIONS

Method for the insertion of protein antigens, of recombinant or synthetic origin, in outer membrane vesicles of Gram-negative bacteria without disruption of the vesicle structure, therefore maintaining the immunogenicity and immunostimulatory properties of said vesicles, and with the reported advant...

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Hauptverfasser: GUILLEN NIETO, GERARDO ENRIQUE, NIEBLA PEREZ, OLIVIA, GARAY PEREZ, HILDA ELISA, DELGADO ESPINA, MAITE, PAJON FEYT, ROLANDO, GONZALEZ BLANCO, SONIA, MARTIN DUNN, ALEJANDRO MIGUEL
Format: Patent
Sprache:eng ; fre
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