ORAL COMPOSITIONS OF FENRETINIDE HAVING INCREASED BIOAVAILABILITY AND METHODS OF USING THE SAME

The present invention provides an edible composition for oral delivery of an active agent such as a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of th...

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Hauptverfasser: REYNOLDS, C. PATRICK, SHAW, WALTER A, MAURER, BARRY JAMES, YESAIR, DAVID W, MCKEE, ROBERT TRAVIS, BURGESS, STEPHEN W
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creator REYNOLDS, C. PATRICK
SHAW, WALTER A
MAURER, BARRY JAMES
YESAIR, DAVID W
MCKEE, ROBERT TRAVIS
BURGESS, STEPHEN W
description The present invention provides an edible composition for oral delivery of an active agent such as a retinide. The composition comprises, in the form of a dry flowable powder: (a) an active agent such as a retinide; (b) lipid matrix composition; (c) optionally sweetener; (d) flour. Compositions of the invention may be administered per se or mixed with a solid or liquid food carrier, for direct oral consumption by a subject or administration through a feeding tube. L'invention concerne une composition comestible permettant de distribuer oralement un agent actif tel qu'un rétinide. Ladite composition comprend, sous forme de poudre fluide sèche: a) un agent actif tel qu'un rétinide; b) une composition matricielle lipidique; c) un édulcorant facultatif; d) de la farine. Les compositions de l'invention peuvent être administrées per se ou mélangées à un support alimentaire solide ou liquide, afin d'être consommées directement oralement par un sujet ou administrées par l'intermédiaire d'un tube d'alimentation.
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subjects FOODS OR FOODSTUFFS
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
title ORAL COMPOSITIONS OF FENRETINIDE HAVING INCREASED BIOAVAILABILITY AND METHODS OF USING THE SAME
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