PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS

In its many embodiments, the present invention provides a novel class of pyrazolo~1,5-a~pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulat...

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Hauptverfasser: GUZI, TIMOTHY J, PARUCH, KAMIL, GIRIJAVALLABHAN, VIYYOOR MOOPIL, JAMES, RAY ANTHONY, HE, ZHEN MIN, DWYER, MICHAEL P, DOLL, RONALD J, TRAN, VINH D, PARK, HAENGSOON, DILLARD, LAWRENCE W
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creator GUZI, TIMOTHY J
PARUCH, KAMIL
GIRIJAVALLABHAN, VIYYOOR MOOPIL
JAMES, RAY ANTHONY
HE, ZHEN MIN
DWYER, MICHAEL P
DOLL, RONALD J
TRAN, VINH D
PARK, HAENGSOON
DILLARD, LAWRENCE W
description In its many embodiments, the present invention provides a novel class of pyrazolo~1,5-a~pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS
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