CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT
The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eucaryontic cells or the fusion of cells, independent of cell division and with reduced cell mort...
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| creator | ALTROGGE, LUDGER CHRISTINE, RAINER RIEMEN, GUDULA LORBACH, ELKE HELFRICH, JULIANA WESSENDORF, HEIKE MUELLER-HARTMANN, HERBERT SIEBENKOTTEN, GREGOR THIEL, CORINNA WEIGEL, MEIKE ROTHMANN, KIRSTEN |
| description | The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eucaryontic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
L'invention concerne une nouvelle configuration de circuit d'électrotransfection ou d'électrofusion permettant de transporter, à l'aide d'un courant électrique, de l'ADN et/ou d'autres molécules biologiquement actives dans le noyau de cellules eucaryotes supérieures ou de fusionner des cellules, indépendamment de la division cellulaire et avec une mortalité cellulaire réduite. |
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L'invention concerne une nouvelle configuration de circuit d'électrotransfection ou d'électrofusion permettant de transporter, à l'aide d'un courant électrique, de l'ADN et/ou d'autres molécules biologiquement actives dans le noyau de cellules eucaryotes supérieures ou de fusionner des cellules, indépendamment de la division cellulaire et avec une mortalité cellulaire réduite.</description><language>eng ; fre</language><subject>APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC,OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWERSUPPLY SYSTEMS ; APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BASIC ELECTRONIC CIRCUITRY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CONTROL OR REGULATION THEREOF ; CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUTPOWER ; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER ; CULTURE MEDIA ; ELECTRICITY ; ELECTROTHERAPY ; ENZYMOLOGY ; GENERATION ; HUMAN NECESSITIES ; HYGIENE ; MAGNETOTHERAPY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; PULSE TECHNIQUE ; RADIATION THERAPY ; SPIRITS ; ULTRASOUND THERAPY ; VINEGAR ; WINE</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141028&DB=EPODOC&CC=CA&NR=2445257C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141028&DB=EPODOC&CC=CA&NR=2445257C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ALTROGGE, LUDGER</creatorcontrib><creatorcontrib>CHRISTINE, RAINER</creatorcontrib><creatorcontrib>RIEMEN, GUDULA</creatorcontrib><creatorcontrib>LORBACH, ELKE</creatorcontrib><creatorcontrib>HELFRICH, JULIANA</creatorcontrib><creatorcontrib>WESSENDORF, HEIKE</creatorcontrib><creatorcontrib>MUELLER-HARTMANN, HERBERT</creatorcontrib><creatorcontrib>SIEBENKOTTEN, GREGOR</creatorcontrib><creatorcontrib>THIEL, CORINNA</creatorcontrib><creatorcontrib>WEIGEL, MEIKE</creatorcontrib><creatorcontrib>ROTHMANN, KIRSTEN</creatorcontrib><title>CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT</title><description>The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eucaryontic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
L'invention concerne une nouvelle configuration de circuit d'électrotransfection ou d'électrofusion permettant de transporter, à l'aide d'un courant électrique, de l'ADN et/ou d'autres molécules biologiquement actives dans le noyau de cellules eucaryotes supérieures ou de fusionner des cellules, indépendamment de la division cellulaire et avec une mortalité cellulaire réduite.</description><subject>APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC,OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWERSUPPLY SYSTEMS</subject><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BASIC ELECTRONIC CIRCUITRY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CONTROL OR REGULATION THEREOF</subject><subject>CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUTPOWER</subject><subject>CONVERSION OR DISTRIBUTION OF ELECTRIC POWER</subject><subject>CULTURE MEDIA</subject><subject>ELECTRICITY</subject><subject>ELECTROTHERAPY</subject><subject>ENZYMOLOGY</subject><subject>GENERATION</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MAGNETOTHERAPY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROCESSES USING MICROORGANISMS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>PULSE TECHNIQUE</subject><subject>RADIATION THERAPY</subject><subject>SPIRITS</subject><subject>ULTRASOUND THERAPY</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjrEOwjAMRLswIOAb8A-wQCvmYNzWKCSS4yB1qioUJgRI8Dv8K6lgZ7rh7t3dtHgjC0ZWMCLGNXQkp1B7AXYHQmXXgItoiREM8j6AcXvw2pLAjr31DaOxtsum8ong6C1htBQyrx5y7ovHAL6GlpsRpIhGOu80lyJZGyCGcYgyqzIWAkaR_GReTC7D9ZkWP50Vy5oU21V63Pv0fAzndEuvHs26LKt1tcXN_8QHn89DSA</recordid><startdate>20141028</startdate><enddate>20141028</enddate><creator>ALTROGGE, LUDGER</creator><creator>CHRISTINE, RAINER</creator><creator>RIEMEN, GUDULA</creator><creator>LORBACH, ELKE</creator><creator>HELFRICH, JULIANA</creator><creator>WESSENDORF, HEIKE</creator><creator>MUELLER-HARTMANN, HERBERT</creator><creator>SIEBENKOTTEN, GREGOR</creator><creator>THIEL, CORINNA</creator><creator>WEIGEL, MEIKE</creator><creator>ROTHMANN, KIRSTEN</creator><scope>EVB</scope></search><sort><creationdate>20141028</creationdate><title>CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT</title><author>ALTROGGE, LUDGER ; CHRISTINE, RAINER ; RIEMEN, GUDULA ; LORBACH, ELKE ; HELFRICH, JULIANA ; WESSENDORF, HEIKE ; MUELLER-HARTMANN, HERBERT ; SIEBENKOTTEN, GREGOR ; THIEL, CORINNA ; WEIGEL, MEIKE ; ROTHMANN, KIRSTEN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2445257C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2014</creationdate><topic>APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC,OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWERSUPPLY SYSTEMS</topic><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BASIC ELECTRONIC CIRCUITRY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CONTROL OR REGULATION THEREOF</topic><topic>CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUTPOWER</topic><topic>CONVERSION OR DISTRIBUTION OF ELECTRIC POWER</topic><topic>CULTURE MEDIA</topic><topic>ELECTRICITY</topic><topic>ELECTROTHERAPY</topic><topic>ENZYMOLOGY</topic><topic>GENERATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MAGNETOTHERAPY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROCESSES USING MICROORGANISMS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>PULSE TECHNIQUE</topic><topic>RADIATION THERAPY</topic><topic>SPIRITS</topic><topic>ULTRASOUND THERAPY</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>ALTROGGE, LUDGER</creatorcontrib><creatorcontrib>CHRISTINE, RAINER</creatorcontrib><creatorcontrib>RIEMEN, GUDULA</creatorcontrib><creatorcontrib>LORBACH, ELKE</creatorcontrib><creatorcontrib>HELFRICH, JULIANA</creatorcontrib><creatorcontrib>WESSENDORF, HEIKE</creatorcontrib><creatorcontrib>MUELLER-HARTMANN, HERBERT</creatorcontrib><creatorcontrib>SIEBENKOTTEN, GREGOR</creatorcontrib><creatorcontrib>THIEL, CORINNA</creatorcontrib><creatorcontrib>WEIGEL, MEIKE</creatorcontrib><creatorcontrib>ROTHMANN, KIRSTEN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ALTROGGE, LUDGER</au><au>CHRISTINE, RAINER</au><au>RIEMEN, GUDULA</au><au>LORBACH, ELKE</au><au>HELFRICH, JULIANA</au><au>WESSENDORF, HEIKE</au><au>MUELLER-HARTMANN, HERBERT</au><au>SIEBENKOTTEN, GREGOR</au><au>THIEL, CORINNA</au><au>WEIGEL, MEIKE</au><au>ROTHMANN, KIRSTEN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT</title><date>2014-10-28</date><risdate>2014</risdate><abstract>The invention relates to a novel circuit arrangement for electrotransfection or electrofusion, which enables the transportation of DNA and/or other biologically active molecules to the nucleus of higher eucaryontic cells or the fusion of cells, independent of cell division and with reduced cell mortality.
L'invention concerne une nouvelle configuration de circuit d'électrotransfection ou d'électrofusion permettant de transporter, à l'aide d'un courant électrique, de l'ADN et/ou d'autres molécules biologiquement actives dans le noyau de cellules eucaryotes supérieures ou de fusionner des cellules, indépendamment de la division cellulaire et avec une mortalité cellulaire réduite.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR CONVERSION BETWEEN AC AND AC, BETWEEN AC AND DC,OR BETWEEN DC AND DC, AND FOR USE WITH MAINS OR SIMILAR POWERSUPPLY SYSTEMS APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BASIC ELECTRONIC CIRCUITRY BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CONTROL OR REGULATION THEREOF CONVERSION OF DC OR AC INPUT POWER INTO SURGE OUTPUTPOWER CONVERSION OR DISTRIBUTION OF ELECTRIC POWER CULTURE MEDIA ELECTRICITY ELECTROTHERAPY ENZYMOLOGY GENERATION HUMAN NECESSITIES HYGIENE MAGNETOTHERAPY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS PULSE TECHNIQUE RADIATION THERAPY SPIRITS ULTRASOUND THERAPY VINEGAR WINE |
| title | CIRCUIT ARRANGEMENT FOR INJECTING NUCLEIC ACIDS AND OTHER BIOLOGICALLY ACTIVE MOLECULES INTO THE NUCLEUS OF HIGHER EUCARYONTIC CELLS USING ELECTRICAL CURRENT |
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