TASTE-MASKED RESINATE AND PREPARATION THEREOF

The present invention is directed to a taste-masked resinate that contains a water-insoluble active substance complexed to an ion-exchange resin in a taste- masking effective amount. The taste-masked resinate is useful in the manufacture of a dosage form such as a rapid-disintegrating tablet, a rapi...

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Hauptverfasser: GREENWOOD, DALE, GOLE, DILIP, MA, LYOU-FU, WILKINSON, PAUL K, DAVIES, JOHN DESMOND, SAVALL, TRACI
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creator GREENWOOD, DALE
GOLE, DILIP
MA, LYOU-FU
WILKINSON, PAUL K
DAVIES, JOHN DESMOND
SAVALL, TRACI
description The present invention is directed to a taste-masked resinate that contains a water-insoluble active substance complexed to an ion-exchange resin in a taste- masking effective amount. The taste-masked resinate is useful in the manufacture of a dosage form such as a rapid-disintegrating tablet, a rapid-disintegrating film, an effervescent tablet, a chewable tablet, a chewing gum, a suspension, a sprinkle granule, a powder for reconstitution in a suspension and the like and a method for the preparation thereof. La présente invention est dirigée vers un resinate au goût masqué qui contient une substance active insoluble dans l'eau complexée à une résine d'échange ionique en une quantité suffisante pour masquer le goût. Le resinate au goût masqué est utile dans la fabrication de comprimés de dosage à désintégration rapide, de comprimés à croquer, de gomme à mâcher, de suspensions, de granules à saupoudrer, d'une poudre pour reconstitution dans une suspension, etc., ainsi que la méthode de préparation de celui-ci.
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subjects CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
HUMAN NECESSITIES
HYGIENE
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TASTE-MASKED RESINATE AND PREPARATION THEREOF
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