AMIDINO COMPOUNDS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS
The present invention relates to amidino compounds of formula (I), in which the variables are as defined in the claims, and salts thereof. In another embodiment the present invention also provides a use of the present compounds as nitric oxide synthase inhibitors. In a further embodiment, the presen...
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| creator | SNYDER, JEFFREY S TOTH, MIHALY V TSYMBALOV, SOFYA SCHARTMAN, RICHARD R TRIVEDI, MAHIMA HAGEN, TIMOTHY J AWASTHI, ALOK K HALLINAN, ANN E TJOENG, FOE SIONG MOORMANN, ALAN E DURLEY, RICHARD C MAO, MICHAEL PHILLIPS, W. GARY FOK, KAM F HANSEN, DONALD W YALAMANCHILI, GOPICHAND VONDER EMBSE, RICHARD WEBBER, RONALD KEITH MANNING, PAMELA T GANSER, SCOTT S BERGMANIS, ARIJA A PROMO, MICHELLE A PITZELE, BARNETT S HICKORY, BRIAN S SCHOLTEN, JEFFREY A |
| description | The present invention relates to amidino compounds of formula (I), in which the variables are as defined in the claims, and salts thereof. In another embodiment the present invention also provides a use of the present compounds as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods for making the amidino compounds and other compounds (I). |
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GARY ; FOK, KAM F ; HANSEN, DONALD W ; YALAMANCHILI, GOPICHAND ; VONDER EMBSE, RICHARD ; WEBBER, RONALD KEITH ; MANNING, PAMELA T ; GANSER, SCOTT S ; BERGMANIS, ARIJA A ; PROMO, MICHELLE A ; PITZELE, BARNETT S ; HICKORY, BRIAN S ; SCHOLTEN, JEFFREY A</creator><creatorcontrib>SNYDER, JEFFREY S ; TOTH, MIHALY V ; TSYMBALOV, SOFYA ; SCHARTMAN, RICHARD R ; TRIVEDI, MAHIMA ; HAGEN, TIMOTHY J ; AWASTHI, ALOK K ; HALLINAN, ANN E ; TJOENG, FOE SIONG ; MOORMANN, ALAN E ; DURLEY, RICHARD C ; MAO, MICHAEL ; PHILLIPS, W. GARY ; FOK, KAM F ; HANSEN, DONALD W ; YALAMANCHILI, GOPICHAND ; VONDER EMBSE, RICHARD ; WEBBER, RONALD KEITH ; MANNING, PAMELA T ; GANSER, SCOTT S ; BERGMANIS, ARIJA A ; PROMO, MICHELLE A ; PITZELE, BARNETT S ; HICKORY, BRIAN S ; SCHOLTEN, JEFFREY A</creatorcontrib><description>The present invention relates to amidino compounds of formula (I), in which the variables are as defined in the claims, and salts thereof. In another embodiment the present invention also provides a use of the present compounds as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods for making the amidino compounds and other compounds (I).</description><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100803&DB=EPODOC&CC=CA&NR=2402199C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100803&DB=EPODOC&CC=CA&NR=2402199C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SNYDER, JEFFREY S</creatorcontrib><creatorcontrib>TOTH, MIHALY V</creatorcontrib><creatorcontrib>TSYMBALOV, SOFYA</creatorcontrib><creatorcontrib>SCHARTMAN, RICHARD R</creatorcontrib><creatorcontrib>TRIVEDI, MAHIMA</creatorcontrib><creatorcontrib>HAGEN, TIMOTHY J</creatorcontrib><creatorcontrib>AWASTHI, ALOK K</creatorcontrib><creatorcontrib>HALLINAN, ANN E</creatorcontrib><creatorcontrib>TJOENG, FOE SIONG</creatorcontrib><creatorcontrib>MOORMANN, ALAN E</creatorcontrib><creatorcontrib>DURLEY, RICHARD C</creatorcontrib><creatorcontrib>MAO, MICHAEL</creatorcontrib><creatorcontrib>PHILLIPS, W. 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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AMIDINO COMPOUNDS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS |
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