PROCESS FOR MAKING GEMINAL BISPHOSPHONATES

The present invention relates to a novel process for making geminal bisphosphonates. The process provides for bisphosphorylation using phosphorus trihalide, phosphorous acid as a reactant/solvent, and a base as an acid acceptor/solvent. The present invention is directed to a process for making gemin...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	CRAMER, WILLIAM DOUGLAS, BILLINGS, DENNIS MICHAEL, CAZER, FREDERICK DANA, PARRY, GREGORY EUGENE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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