OSMOTIC DEVICE CONTAINING PSEUDOEPHEDRINE AND AN H1 ANTAGONIST

OSMOTIC DEVICE CONTAINING PSEUDOEPHEDRINE AND AN H1 ANTAGONIST

The present invention provides an osmotic device containing controlled relea se pseudoephedrine in the core in combination with a rapid release H1 antagonis t in an external coat. A wide range of H1 antagonist antihistamines, especiall y fexofenadine, can be used in this device. Particular embodimen...

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Hauptverfasser: FAOUR, JOAQUINA, RICCI, MARCELO A
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Sprache:eng ; fre
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator FAOUR, JOAQUINA
RICCI, MARCELO A
description The present invention provides an osmotic device containing controlled relea se pseudoephedrine in the core in combination with a rapid release H1 antagonis t in an external coat. A wide range of H1 antagonist antihistamines, especiall y fexofenadine, can be used in this device. Particular embodiments of the invention provide osmotic devices having predetermined release profiles. One embodiment of the osmotic device includes an external coat that has been spr ay coated rather than compression coated onto the device. The device with spray coated external core is smaller and easier to swallow than the similar devic e having a compression coated external coat. The device is useful for the treatment of respiratory congestion related disorders and allergy related disorders. The present devices provide PS and an H1 antagonist according to specific release profiles in combination with specific formulations.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title OSMOTIC DEVICE CONTAINING PSEUDOEPHEDRINE AND AN H1 ANTAGONIST
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