HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE
The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1...
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creator | PORCS-MAKKAY, MARTA SIMIG, GYULA NEMETH, NORBERT VERECZKEYNE DONATH, GYORGYI NAGY, KALMAN BUDAI, ZOLTAN LUKACS, GYULA MEZEI, TIBOR KRASZNAI, GYORGY SZABO, TIBOR SZULAGYI, JANOS |
description | The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use. |
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Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</description><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2010</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100706&DB=EPODOC&CC=CA&NR=2369393C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20100706&DB=EPODOC&CC=CA&NR=2369393C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PORCS-MAKKAY, MARTA</creatorcontrib><creatorcontrib>SIMIG, GYULA</creatorcontrib><creatorcontrib>NEMETH, NORBERT</creatorcontrib><creatorcontrib>VERECZKEYNE DONATH, GYORGYI</creatorcontrib><creatorcontrib>NAGY, KALMAN</creatorcontrib><creatorcontrib>BUDAI, ZOLTAN</creatorcontrib><creatorcontrib>LUKACS, GYULA</creatorcontrib><creatorcontrib>MEZEI, TIBOR</creatorcontrib><creatorcontrib>KRASZNAI, GYORGY</creatorcontrib><creatorcontrib>SZABO, TIBOR</creatorcontrib><creatorcontrib>SZULAGYI, JANOS</creatorcontrib><title>HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE</title><description>The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2010</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFjk9Lw0AQxevBg6ifwbnZYraQRCw9Tncn3YX9x-4GDSGUIvEkWqg38bu70R4FT2_mzW_ezMXZnVRbCb4NKnUwL0NRxeI-LNicLVjF-nl1yz5tYZlQhpLsNBpl3RfLtXvqFsPEeEm20wMri1WxYiko1v-yA9so3nHt-mpZLctBkk9oCdAK8BKDQU5tUhy17gA5n8YbnedcCUAhVFLOQkSdIiRJgVxTgA-OU4zQuDCZuSePAX9Q10xWJODOeNdaEQEjPJLWkxoS-ZYhm-O4swmVVXYLJeQk4wL9uZ5fzZ4K0Ea6mp2_7F-P4_VJL2c3DSUu2Xh4343Hw_55fBs_dhyr-mFdr2te_098A2ubZ4k</recordid><startdate>20100706</startdate><enddate>20100706</enddate><creator>PORCS-MAKKAY, MARTA</creator><creator>SIMIG, GYULA</creator><creator>NEMETH, NORBERT</creator><creator>VERECZKEYNE DONATH, GYORGYI</creator><creator>NAGY, KALMAN</creator><creator>BUDAI, ZOLTAN</creator><creator>LUKACS, GYULA</creator><creator>MEZEI, TIBOR</creator><creator>KRASZNAI, GYORGY</creator><creator>SZABO, TIBOR</creator><creator>SZULAGYI, JANOS</creator><scope>EVB</scope></search><sort><creationdate>20100706</creationdate><title>HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE</title><author>PORCS-MAKKAY, MARTA ; SIMIG, GYULA ; NEMETH, NORBERT ; VERECZKEYNE DONATH, GYORGYI ; NAGY, KALMAN ; BUDAI, ZOLTAN ; LUKACS, GYULA ; MEZEI, TIBOR ; KRASZNAI, GYORGY ; SZABO, TIBOR ; SZULAGYI, JANOS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2369393C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2010</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PORCS-MAKKAY, MARTA</creatorcontrib><creatorcontrib>SIMIG, GYULA</creatorcontrib><creatorcontrib>NEMETH, NORBERT</creatorcontrib><creatorcontrib>VERECZKEYNE DONATH, GYORGYI</creatorcontrib><creatorcontrib>NAGY, KALMAN</creatorcontrib><creatorcontrib>BUDAI, ZOLTAN</creatorcontrib><creatorcontrib>LUKACS, GYULA</creatorcontrib><creatorcontrib>MEZEI, TIBOR</creatorcontrib><creatorcontrib>KRASZNAI, GYORGY</creatorcontrib><creatorcontrib>SZABO, TIBOR</creatorcontrib><creatorcontrib>SZULAGYI, JANOS</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PORCS-MAKKAY, MARTA</au><au>SIMIG, GYULA</au><au>NEMETH, NORBERT</au><au>VERECZKEYNE DONATH, GYORGYI</au><au>NAGY, KALMAN</au><au>BUDAI, ZOLTAN</au><au>LUKACS, GYULA</au><au>MEZEI, TIBOR</au><au>KRASZNAI, GYORGY</au><au>SZABO, TIBOR</au><au>SZULAGYI, JANOS</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE</title><date>2010-07-06</date><risdate>2010</risdate><abstract>The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE |
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