HIGH PURITY (1R,2S,4R)-(-)-2-[(2'-{N,N-DIMETHYLAMINO}-ETHOXY)]-2-[PHENYL]-1,7,7-TRI-[METHYL]-BICYCLO[2.2.1]HEPTANE AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AS WELL AS MEDICAMENTS CONTAINING 1 OR MORE OF THESE COMPOUNDS AND THEIR USE

The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1...

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Hauptverfasser: PORCS-MAKKAY, MARTA, SIMIG, GYULA, NEMETH, NORBERT, VERECZKEYNE DONATH, GYORGYI, NAGY, KALMAN, BUDAI, ZOLTAN, LUKACS, GYULA, MEZEI, TIBOR, KRASZNAI, GYORGY, SZABO, TIBOR, SZULAGYI, JANOS
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The invention relates to high purity (1R,2S,4R)-(-)-2- [(2'-{N,N-dimethylamino} -ethoxy)] -2-[phenyl] -1,7,7-tri-[methyl] -bicyclo[2.2.1] heptane and pharmaceutically acceptable acid addition salts thereof containing not more than 0.2 % of (1R,3S,4R)-3- [(2'-{N,N- dimethylamino} -ethyl)]-1,7,7-tri- [methyl] -bicyclo [2.2.1] heptane-2-one and/or of a pharmaceutically acceptable acid addition salt thereof. Furthermore the invention is concerned with a process for the preparation of these compounds. Moreover the invention relates to medicaments containing 1 or more of these compounds and their use.