AMINO-THIO-ACRYLONITRILES AS MEK INHIBITORS

This invention relates generally to amino-thio-acrylonitriles of formula (Ia ) or (Ib) as MEK inhibitors, pharmaceutical compositions containing the same, and methods of using the same as for treatment and prevention of inflammator y disorders or as an anticancer radiosensitizing agent.

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Bibliographische Detailangaben
1. Verfasser:	HOBBS, FRANK W
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates generally to amino-thio-acrylonitriles of formula (Ia ) or (Ib) as MEK inhibitors, pharmaceutical compositions containing the same, and methods of using the same as for treatment and prevention of inflammator y disorders or as an anticancer radiosensitizing agent.