REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE BREAST
A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as BS322 and transcribed from breast tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating...
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| creator | FRIEDMAN, PAULA N RUSSELL, JOHN C HODGES, STEVEN C BILLING-MEDEL, PATRICIA A GORDON, JULIAN STROUPE, STEPHEN D COLPITTS, TRACEY L KRATOCHVIL, JON D KLASS, MICHAEL R COHEN, MAURICE GRANADOS, EDWARD N |
| description | A set of contiguous and partially overlapping cDNA sequences and polypeptides encoded thereby, designated as BS322 and transcribed from breast tissue, is described. These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast, such as breast cancer. Also provided are antibodies which specifically bind to BS322-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BS322 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases. |
| format | Patent |
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These sequences are useful for the detecting, diagnosing, staging, monitoring, prognosticating, in vivo imaging, preventing or treating, or determining the predisposition of an individual to diseases and conditions of the breast, such as breast cancer. Also provided are antibodies which specifically bind to BS322-encoded polypeptide or protein, and agonists or inhibitors which prevent action of the tissue-specific BS322 polypeptide, which molecules are useful for the therapeutic treatment of breast diseases, tumors or metastases.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | REAGENTS AND METHODS USEFUL FOR DETECTING DISEASES OF THE BREAST |
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