HUMAN ANTI-FACTOR IX/IXA ANTIBODIES

Human antibodies, or fragments thereof, to the gamma-carboxyglutamic acid (Gla) domain of factor IX and factor IXa, especially of human factor IX and human factor IXa. Isolated nucleic acid encoding said antibodies or fragments thereof. Methods for their preparation. Pharmaceutical composition compr...

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Bibliographische Detailangaben
Hauptverfasser: HASS, PHILIP E, KIRCHHOFER, DANIEL, ADAMS, CAMELLIA W, JUDICE, J. KEVIN, SUGGETT, SHELLEY, DEVAUX, BRIGITTE, EATON, DAN L
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Human antibodies, or fragments thereof, to the gamma-carboxyglutamic acid (Gla) domain of factor IX and factor IXa, especially of human factor IX and human factor IXa. Isolated nucleic acid encoding said antibodies or fragments thereof. Methods for their preparation. Pharmaceutical composition comprising said antibodies or fragments thereof, and a method for treating a mammal by using said pharmaceutical composition in a therapeutically effective amount.