IMMUNOASSAY TO DETECT HERPESVIRUS SPECIFIC IGM
This invention provides a method, a reagent, and a kit for detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The invention also provides a reagent for use in...
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| creator | MAINE, GREGORY T |
| description | This invention provides a method, a reagent, and a kit for detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The invention also provides a reagent for use in detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The method of this invention comprises the steps of: (a) providing a solid phase containing at least a portion of a herpesvirus antigen; (b) introducing a patient specimen to the solid phase of step (a); (c) introducing at least one peptide capable of specifically binding Ig M antibodies to herpesvirus to the solid phase of step (a); (d) allowing IgM antibodies to herpesvirus to specifically bind to the portion o f antigen of herspesvirus and the peptide capable of specifically binding IgM antibodies to herpesvirus to the solid phase; and (e) determinin g the level of IgM antibodies to herspesvirus in the patient specimen. |
| format | Patent |
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The invention also provides a reagent for use in detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The method of this invention comprises the steps of: (a) providing a solid phase containing at least a portion of a herpesvirus antigen; (b) introducing a patient specimen to the solid phase of step (a); (c) introducing at least one peptide capable of specifically binding Ig M antibodies to herpesvirus to the solid phase of step (a); (d) allowing IgM antibodies to herpesvirus to specifically bind to the portion o f antigen of herspesvirus and the peptide capable of specifically binding IgM antibodies to herpesvirus to the solid phase; and (e) determinin g the level of IgM antibodies to herspesvirus in the patient specimen.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; TESTING ; VINEGAR ; WINE</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090414&DB=EPODOC&CC=CA&NR=2304980C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090414&DB=EPODOC&CC=CA&NR=2304980C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MAINE, GREGORY T</creatorcontrib><title>IMMUNOASSAY TO DETECT HERPESVIRUS SPECIFIC IGM</title><description>This invention provides a method, a reagent, and a kit for detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The invention also provides a reagent for use in detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The method of this invention comprises the steps of: (a) providing a solid phase containing at least a portion of a herpesvirus antigen; (b) introducing a patient specimen to the solid phase of step (a); (c) introducing at least one peptide capable of specifically binding Ig M antibodies to herpesvirus to the solid phase of step (a); (d) allowing IgM antibodies to herpesvirus to specifically bind to the portion o f antigen of herspesvirus and the peptide capable of specifically binding IgM antibodies to herpesvirus to the solid phase; and (e) determinin g the level of IgM antibodies to herspesvirus in the patient specimen.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>TESTING</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDz9PUN9fN3DA52jFQI8VdwcQ1xdQ5R8HANCnANDvMMCg1WCA5wdfZ083RW8HT35WFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORsYGJpYWBs7GhFUAAGikJQQ</recordid><startdate>20090414</startdate><enddate>20090414</enddate><creator>MAINE, GREGORY T</creator><scope>EVB</scope></search><sort><creationdate>20090414</creationdate><title>IMMUNOASSAY TO DETECT HERPESVIRUS SPECIFIC IGM</title><author>MAINE, GREGORY T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA2304980C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2009</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>TESTING</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>MAINE, GREGORY T</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAINE, GREGORY T</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMMUNOASSAY TO DETECT HERPESVIRUS SPECIFIC IGM</title><date>2009-04-14</date><risdate>2009</risdate><abstract>This invention provides a method, a reagent, and a kit for detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The invention also provides a reagent for use in detecting herpesvirus-specific IgM antibodies indicative of recent infection while preventing detection of low levels of herpesvirus-specific IgM antibodies present in individuals of low risk. The method of this invention comprises the steps of: (a) providing a solid phase containing at least a portion of a herpesvirus antigen; (b) introducing a patient specimen to the solid phase of step (a); (c) introducing at least one peptide capable of specifically binding Ig M antibodies to herpesvirus to the solid phase of step (a); (d) allowing IgM antibodies to herpesvirus to specifically bind to the portion o f antigen of herspesvirus and the peptide capable of specifically binding IgM antibodies to herpesvirus to the solid phase; and (e) determinin g the level of IgM antibodies to herspesvirus in the patient specimen.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | IMMUNOASSAY TO DETECT HERPESVIRUS SPECIFIC IGM |
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