2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS AMPA-RECEPTOR INHIBITORS

2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS AMPA-RECEPTOR INHIBITORS

The invention concerns compounds of formula (I), in which: X designates hydrogen or halogen; Y designates -NR3- or -N=; R1, R2 and R3 designate hydrogen or different substituents; R4 designates optionall y substituted C1-C6 alkyl; R5 designates hydrogen; or R4 and R5 together designate oxygen; R6 de...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: CSUZDI, EMESE, TARNAWA, ISTVAN, SIMAY, ANTAL, ANDRASI, FERENC, ABRAHAM, GIZELLA, SOLYOM, SANDOR, PALLAGI, ISTVAN, SZOLLOSY, MARTA, LING, ISTVAN, BERZSENYI, PAL, HORVATH, KATALIN, HAMORI, TAMAS
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention concerns compounds of formula (I), in which: X designates hydrogen or halogen; Y designates -NR3- or -N=; R1, R2 and R3 designate hydrogen or different substituents; R4 designates optionall y substituted C1-C6 alkyl; R5 designates hydrogen; or R4 and R5 together designate oxygen; R6 designates C1-C4 alkyl; and (a) designates a double bond or single bonds. Owing to their non-competitive inhibiting of the AMPA receptors, these compounds can be used as medicaments for treating diseases of the central nervous system.