METHODS FOR THE PRODUCTION OF PLATINUM-BASED LINKERS BETWEENLABELS AND BIO-ORGANIC MOLECULES, FOR LABELLING BIO-ORGANIC MOLECULES, FOR DETECTING BIOLOGICAL SUBSTANCES OF INTERESTAND DIAGNOSTIC TEST KITS

The present invention provides improved methods of producing platinum compounds, which are very suitable for producing labelled substances, which can be used to detect specific molecules of interest. The platinum coordination compounds have two reactive groups of which one is replaced by a label and...

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Hauptverfasser: REEDIJK, JAN, VAN DEN BERG, FRANCISCUS MICHIEL, HOUTHOFF, HENDRIK JAN, VAN ES, REMCO MARIA, LEMPERS, EDWIN LEO MARIO, BLOEMINK, MARIEKE JOHANNA, JELSMA, TINKA
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creator REEDIJK, JAN
VAN DEN BERG, FRANCISCUS MICHIEL
HOUTHOFF, HENDRIK JAN
VAN ES, REMCO MARIA
LEMPERS, EDWIN LEO MARIO
BLOEMINK, MARIEKE JOHANNA
JELSMA, TINKA
description The present invention provides improved methods of producing platinum compounds, which are very suitable for producing labelled substances, which can be used to detect specific molecules of interest. The platinum coordination compounds have two reactive groups of which one is replaced by a label and the other one can be replaced by a substance to be labelled. Production of labelled substances is very much improved by selection of the right starting materials and producing the right intermediates. The efficiency of labelling is very much improved, thereby enabling the production of labelling kits which are also a part of the present invention.
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The platinum coordination compounds have two reactive groups of which one is replaced by a label and the other one can be replaced by a substance to be labelled. Production of labelled substances is very much improved by selection of the right starting materials and producing the right intermediates. 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The platinum coordination compounds have two reactive groups of which one is replaced by a label and the other one can be replaced by a substance to be labelled. Production of labelled substances is very much improved by selection of the right starting materials and producing the right intermediates. The efficiency of labelling is very much improved, thereby enabling the production of labelling kits which are also a part of the present invention.</abstract><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
ADHESIVES
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
DERIVATIVES THEREOF
DYES
ENZYMOLOGY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
LAKES
MEASURING
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MISCELLANEOUS APPLICATIONS OF MATERIALS
MISCELLANEOUS COMPOSITIONS
MORDANTS
MUTATION OR GENETIC ENGINEERING
NATURAL RESINS
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES
PAINTS
PEPTIDES
PHYSICS
POLISHES
PROCESSES OF PREPARING SUCH COMPOSITIONS
SPIRITS
SUGARS
TESTING
VINEGAR
WINE
title METHODS FOR THE PRODUCTION OF PLATINUM-BASED LINKERS BETWEENLABELS AND BIO-ORGANIC MOLECULES, FOR LABELLING BIO-ORGANIC MOLECULES, FOR DETECTING BIOLOGICAL SUBSTANCES OF INTERESTAND DIAGNOSTIC TEST KITS
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