FELINE INFECTIOUS PERITONITIS VACCINE

The invention comprises the nucleotide sequences comprising the FIPV S gene, or a fragment of this gene, which are modified in at least one of the antigenic regions Al and A2 which are involved in enhancement, as well as the use of these sequences for the expression of modified proteins, and for the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CORAPI, WAYNE, CHAPPUIS, GILLES-EMILE, DARTEIL, RAPHAEL, AUDONNET, JEANIRSTOPHE FRANCIS
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The invention comprises the nucleotide sequences comprising the FIPV S gene, or a fragment of this gene, which are modified in at least one of the antigenic regions Al and A2 which are involved in enhancement, as well as the use of these sequences for the expression of modified proteins, and for the construction of recombinant viruses or expression plasmids, and the use of the recombinant viruses as vaccines against feline infectious peritonitis, the use of the expression plasmids as immunizing composition by direct injection of the said plasmids into cats, and the use of the modified proteins as vaccine.