LANTHIONINE-CONTAINING ANTIMICROBIAL COMPOUND

A lanthionine-containing antimicrobial peptide obtainable from Staphylococcus hyicus strain 664 and pharmaceutically acceptable acid addition salts thereof as well as pharmaceutical compositions comprising said peptide or its acid addition salts and DNA molecules encoding said peptide are described....

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Hauptverfasser: PEEL, JOHN EDMONDSON, RASCHDORF, FRITZ, SCHNEIDER, JOSEF, SURI, BRUNO
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creator PEEL, JOHN EDMONDSON
RASCHDORF, FRITZ
SCHNEIDER, JOSEF
SURI, BRUNO
description A lanthionine-containing antimicrobial peptide obtainable from Staphylococcus hyicus strain 664 and pharmaceutically acceptable acid addition salts thereof as well as pharmaceutical compositions comprising said peptide or its acid addition salts and DNA molecules encoding said peptide are described. The peptide is purified from the culture medium of Staphylococcus hyicus strain 664 and can be used in a method of treating or preventing mastitis in a mammal comprising administering to said mammal a pharmaceutically effective amount of the peptide or a pharmaceutically acceptable acid addition salt thereof to effectively treat mastitis or effectively to suppress the rate, severity, and duration of subsequent bacterial infection.
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The peptide is purified from the culture medium of Staphylococcus hyicus strain 664 and can be used in a method of treating or preventing mastitis in a mammal comprising administering to said mammal a pharmaceutically effective amount of the peptide or a pharmaceutically acceptable acid addition salt thereof to effectively treat mastitis or effectively to suppress the rate, severity, and duration of subsequent bacterial infection.</description><edition>6</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; DERIVATIVES THEREOF ; ENZYMOLOGY ; FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROCESSES USING MICROORGANISMS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; SUGARS ; VINEGAR ; WINE</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951116&amp;DB=EPODOC&amp;CC=CA&amp;NR=2186621A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19951116&amp;DB=EPODOC&amp;CC=CA&amp;NR=2186621A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PEEL, JOHN EDMONDSON</creatorcontrib><creatorcontrib>RASCHDORF, FRITZ</creatorcontrib><creatorcontrib>SCHNEIDER, JOSEF</creatorcontrib><creatorcontrib>SURI, BRUNO</creatorcontrib><title>LANTHIONINE-CONTAINING ANTIMICROBIAL COMPOUND</title><description>A lanthionine-containing antimicrobial peptide obtainable from Staphylococcus hyicus strain 664 and pharmaceutically acceptable acid addition salts thereof as well as pharmaceutical compositions comprising said peptide or its acid addition salts and DNA molecules encoding said peptide are described. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
DERIVATIVES THEREOF
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
SUGARS
VINEGAR
WINE
title LANTHIONINE-CONTAINING ANTIMICROBIAL COMPOUND
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