NOVEL 1,2-DITHIIN ANTIINFECTIVE AGENTS

This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida albicans, Crytococus neoformans or Aspergill...

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Hauptverfasser: BIERER, DONALD E, DENER, JEFFREY M, TEMPESTA, MICHAEL S, KOREEDA, MASATO, HECTOR, RICHARD, TRUONG, THIEN V, YANG, WU, LOEV, BERNARD
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creator BIERER, DONALD E
DENER, JEFFREY M
TEMPESTA, MICHAEL S
KOREEDA, MASATO
HECTOR, RICHARD
TRUONG, THIEN V
YANG, WU
LOEV, BERNARD
description This invention pertains to a novel group of 1,2-dithiin compounds useful as antiinfective agents, and a novel synthetic process to produce the same. The compounds are particularly effective in treating fungal infections, especially those caused by Candida albicans, Crytococus neoformans or Aspergillus fumigatus. L'invention a pour objet un nouveau groupe de composés de 1,2-dithiine utilisables comme agents anti-infectieux, ainsi qu'un nouveau procédé de synthèse pour produire ceux-ci. Ces composés sont particulièrement efficaces pour traiter les mycoses, en particulier celles dues à Candida albicans, Cryptococcus neoformans et Aspergillus fumigatus.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title NOVEL 1,2-DITHIIN ANTIINFECTIVE AGENTS
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