COMPOSITIONS FOR INHALATION

Pharmaceutical compositions containing a mixture of a pharmaceutically activ e polypeptide and an enhancer compound which enhances the systemic absorption of the polypeptide in the lung of a patient, the mixture being in the form of a dry powder, in which at least 50 % of the total mass of polypepti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BACKSTROM, KJELL GORAN ERIK, EDMAN, PETER, JOHANSSON, ANN CHARLOTTE BIRGIT, DAHLBACK, CARL MAGNUS OLOF
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:Pharmaceutical compositions containing a mixture of a pharmaceutically activ e polypeptide and an enhancer compound which enhances the systemic absorption of the polypeptide in the lung of a patient, the mixture being in the form of a dry powder, in which at least 50 % of the total mass of polypeptide and enhancer consists of primary particles having a diameter less than or equal to about 10 microns, the primary particles optionally being formed into agglomerates; and methods of delivering such compositions by inhalation.