PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE
The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpireridine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3-benzylaminopoperidines that can...
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Sprache: | eng ; fre |
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Zusammenfassung: | The present invention relates to a novel process for preparing and resolving 3-amino-2-phenylpireridine and for synthesizing from the enantiomers of such compound certain pharmaceutically active substituted 2-phenyl-3-benzylaminopiperidines. The substituted 2-phenyl-3-benzylaminopoperidines that can be prepared by the processes of this invention are substance P receptor antagonists and are useful in the treatment and prevention of inflammatory and central nervous system disorders, as well as several other disorders. |
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