BIOACTIVE AND/OR TARGETED DENDRIMER CONJUGATES

Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present,...

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Hauptverfasser: TOMLINSON, IAN A, BROTHERS, HERBERT M., II, KUKOWSKA-LATALLO, JOLANTA, TOMALIA, DONALD A, JOHNSON, JENNIFER A, WILSON, LARRY R, KAPLAN, DONALD A, MAXON, BARTLEY D, YIN, RUI, HEDSTRAND, DAVID M, BIELINSKA, ANNA U, FAZIO, MICHAEL J, KRUPER, WILLIAM J., JR, BAKER, JAMES R, CHENG, ROBERTA C, KLAKAMP, SCOTT L, PIEHLER, LARS T
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Sprache:eng ; fre
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Zusammenfassung:Dendritic polymer conjugates which are composed of at least one dendrimer in association with at least one unit of a carried material, where the carrier material can be a biological response modifier, have been prepared. The conjugate can also have a target director present, and when it is present, then the carried material may be a bioactive agent. Preferred dendritic polymers are dense starr polymers, which have been complexed with biological response modifiers. These conjugates and complexes have particularly advantageous properties due to their unique characteristics.