ORAL PREPARATION FOR RELEASE IN LOWER DIGESTIVE TRACTS

An oral pharmaceutical preparation of a type released at infragastrointestinal tract was successfully prepared, wherein a solid organic acid dissolvable, in the form of a solution, of chitosan and a solid pharmaceutical preparation including a principal agent are filled in a hard capsule composed of...

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Bibliographische Detailangaben
Hauptverfasser: FUJISAWA, MISUZU, YAMADA, AKIYA, INAMOTO, YUKIKO, UCHIA, NAOKI, WATO, TAKAHIKO, TAKAMA, SHIGEYUKI
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:An oral pharmaceutical preparation of a type released at infragastrointestinal tract was successfully prepared, wherein a solid organic acid dissolvable, in the form of a solution, of chitosan and a solid pharmaceutical preparation including a principal agent are filled in a hard capsule composed of the base principall y comprising chitosan and an enteric coating is formed on the surface of the hard capsule, characterized in that a desirable releasing time can be arranged, with no pH dependency, via water permeability derived from the porosity of chitosan of the capsule preparation.