HTLV-I/HTLV-II ASSAY AND METHOD

Method and assay kit for positively identifying HTLV-I and HTLV-II infection from human serum samples. The kit includes peptide antigens from the C-terminal regions of HTLV-I p19 and HTLV -II p21 gag proteins, and peptide antigens from the HTLV-I and HTLV-II env proteins immobilized on a solid suppo...

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Bibliographische Detailangaben
Hauptverfasser:	HADLOCK, KENNETH G, CHOW, THERESA P, FOUNG, STEVEN K. H
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Method and assay kit for positively identifying HTLV-I and HTLV-II infection from human serum samples. The kit includes peptide antigens from the C-terminal regions of HTLV-I p19 and HTLV -II p21 gag proteins, and peptide antigens from the HTLV-I and HTLV-II env proteins immobilized on a solid support. After re action of the serum sample with the solid support, an antibody-detection reagent in the kit is added to the support, to detect binding of human serum antibodies to each of the peptide antigens separately. The test allows positive identification of HTLV -I or HTLV-II when antibody binding to each HTLV-I or HTLV-II gag and env peptide antigen, respectively, is observed. Also disclos ed is a kit for screening human sera for evidence of HTLV-I or HTLV-II infection.