2- AND 3-AMINO AND AZIDO DERIVATIVES OF 1,5-IMINOSUGARS

Novel derivatives of 1-deoxynojirimycin are disclosed which have amino or azido substituents at C-2 and/or C-3. These compounds are useful inhibitors of lentiviruses. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.

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Hauptverfasser: KHANNA, ISH KUMAR, WEIER, RICHARD MATHIAS, MUELLER, RICHARD AUGUST, STEALEY, MICHAEL ALLAN
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creator KHANNA, ISH KUMAR
WEIER, RICHARD MATHIAS
MUELLER, RICHARD AUGUST
STEALEY, MICHAEL ALLAN
description Novel derivatives of 1-deoxynojirimycin are disclosed which have amino or azido substituents at C-2 and/or C-3. These compounds are useful inhibitors of lentiviruses. Methods of chemical synthesis of these derivatives and intermediates therefor are also disclosed.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title 2- AND 3-AMINO AND AZIDO DERIVATIVES OF 1,5-IMINOSUGARS
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