METHOD FOR DETECTING BOVINE DIARRHOEA VIRUS INFECTION NUCLEOTIDE SEQUENCE ENCODING A PROTEIN INDUCED BY THIS VIRUS INFECTION AND RECOMBINANT PROTEINS AND ANTIGENS RELATING THERETO

A method for detecting infection of a blood sample by a bovine diarrhoea virus (BVD). The method comprises a first test for the detection of anti-BVD antibodies and a second test for the detection of viral particles. The tests are characterised in that the anti-p80 antibodies are detected by means o...

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Hauptverfasser: VANDENBERGH, DANIELLE MARIE HELENE JEANNE, CHAPPUIS, GILLES-EMILE, LECOMTE, CORINE MARTINE THERESE GHISLAINE, PIN, JEAN-JACQUES
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:A method for detecting infection of a blood sample by a bovine diarrhoea virus (BVD). The method comprises a first test for the detection of anti-BVD antibodies and a second test for the detection of viral particles. The tests are characterised in that the anti-p80 antibodies are detected by means of a recombinant antigen comprising the HVD virus protein p80 produced in a eukaryotic host, and in that the presence of viral particles is detected by means of antibodies directed against the BVD virus protein p80, for the detection of persistent viremiae and acute infections by any BVD strain. Also within the scope of the invention is a nucleotide sequence corresponding to the BVD Osloss sequence encoding the non-structural protein p80 and a recombinant protein corresponding to the translation of this nucleotide sequence.