AZABICYCLO DERIVATIVES

Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: (see formula I) wherein A is a group of formula (a), (b) or (c): (see formula a, b or c) wherein R1 is hydrogen, C1-C10 alkyl, aralkyl or di(C1-C4) alkylamino(C1-C6)alkyl; R2, R3 and R4 may be the same or different...

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Hauptverfasser:	HAYAKAWA, TORU, YAHATA, NOBUHIRO, KIKUCHI, HARUHIKO, MINO, SETSUKO, HAGIHARA, KOICHIRO, SATOH, HIROAKI, YANAI, MAKOTO
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Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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creator	HAYAKAWA, TORU YAHATA, NOBUHIRO KIKUCHI, HARUHIKO MINO, SETSUKO HAGIHARA, KOICHIRO SATOH, HIROAKI YANAI, MAKOTO
description	Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: (see formula I) wherein A is a group of formula (a), (b) or (c): (see formula a, b or c) wherein R1 is hydrogen, C1-C10 alkyl, aralkyl or di(C1-C4) alkylamino(C1-C6)alkyl; R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1-C4 alkoxy or phthalimide; X is O or NH; R is C1-C4 alkyl; and Y is NR, O or S; having 5-HT3 receptor antagonist activity.
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R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1-C4 alkoxy or phthalimide; X is O or NH; R is C1-C4 alkyl; and Y is NR, O or S; having 5-HT3 receptor antagonist activity.</description><edition>5</edition><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2001</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010605&DB=EPODOC&CC=CA&NR=2047848C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20010605&DB=EPODOC&CC=CA&NR=2047848C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAYAKAWA, TORU</creatorcontrib><creatorcontrib>YAHATA, NOBUHIRO</creatorcontrib><creatorcontrib>KIKUCHI, HARUHIKO</creatorcontrib><creatorcontrib>MINO, SETSUKO</creatorcontrib><creatorcontrib>HAGIHARA, KOICHIRO</creatorcontrib><creatorcontrib>SATOH, HIROAKI</creatorcontrib><creatorcontrib>YANAI, MAKOTO</creatorcontrib><title>AZABICYCLO DERIVATIVES</title><description>Azabicyclo derivatives of formula (I) and pharmaceutically acceptable salts thereof: (see formula I) wherein A is a group of formula (a), (b) or (c): (see formula a, b or c) wherein R1 is hydrogen, C1-C10 alkyl, aralkyl or di(C1-C4) alkylamino(C1-C6)alkyl; R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1-C4 alkoxy or phthalimide; X is O or NH; R is C1-C4 alkyl; and Y is NR, O or S; having 5-HT3 receptor antagonist activity.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2001</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBBzjHJ08nSOdPbxV3BxDfIMcwzxDHMN5mFgTUvMKU7lhdLcDPJuriHOHrqpBfnxqcUFicmpeakl8c6ORgYm5hYmFs7GhFUAAEkqHmw</recordid><startdate>20010605</startdate><enddate>20010605</enddate><creator>HAYAKAWA, TORU</creator><creator>YAHATA, NOBUHIRO</creator><creator>KIKUCHI, HARUHIKO</creator><creator>MINO, SETSUKO</creator><creator>HAGIHARA, KOICHIRO</creator><creator>SATOH, HIROAKI</creator><creator>YANAI, MAKOTO</creator><scope>EVB</scope></search><sort><creationdate>20010605</creationdate><title>AZABICYCLO DERIVATIVES</title><author>HAYAKAWA, TORU ; 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R2, R3 and R4 may be the same or different and each is hydrogen, amino, halogen, C1-C4 alkoxy or phthalimide; X is O or NH; R is C1-C4 alkyl; and Y is NR, O or S; having 5-HT3 receptor antagonist activity.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record>
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
title	AZABICYCLO DERIVATIVES
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