PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT

A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic...

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creator BELLASIO, ELVIO
description A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic inert organic solvent or a mixture thereof at a temperature between 20.degree.C and the boiling temperature by the reaction mixture. The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT
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