PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT
A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic...
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creator | BELLASIO, ELVIO |
description | A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic inert organic solvent or a mixture thereof at a temperature between 20.degree.C and the boiling temperature by the reaction mixture. The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof. |
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The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof.</description><edition>6</edition><language>eng ; fre</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980922&DB=EPODOC&CC=CA&NR=1340055C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19980922&DB=EPODOC&CC=CA&NR=1340055C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BELLASIO, ELVIO</creatorcontrib><title>PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT</title><description>A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic inert organic solvent or a mixture thereof at a temperature between 20.degree.C and the boiling temperature by the reaction mixture. The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqFyjEOwjAMQNEsDAg4A74AUlHpAVwroZHADo47MFUVChOCSuX-goGd6b_hL90lqZDPGYIoWOchqU-oaFEYJIB5tYh6BUJtI8spAwkbRo58RAY8f0WQ-zZbtN6zrd3iPj7msvl15bbBG3W7Mr2GMk_jrTzLeyDc14eqahqq_x8fFZIuyA</recordid><startdate>19980922</startdate><enddate>19980922</enddate><creator>BELLASIO, ELVIO</creator><scope>EVB</scope></search><sort><creationdate>19980922</creationdate><title>PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT</title><author>BELLASIO, ELVIO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA1340055C3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1998</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BELLASIO, ELVIO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BELLASIO, ELVIO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT</title><date>1998-09-22</date><risdate>1998</risdate><abstract>A process for the preparation of tertiary diphenyl carbinols containing a primary or secondary amine substituent on the aliphatic moiety attached to the carbinol function which consists in contacting a Grignard phenyl reagent with an amino-acid wherein the mobile protons are not masked in an aprotic inert organic solvent or a mixture thereof at a temperature between 20.degree.C and the boiling temperature by the reaction mixture. The reaction products are useful as active ingredients of medicaments and intermediates for the manufacture thereof.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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language | eng ; fre |
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subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | PROCESS FOR THE PREPARATION OF TERTIARY CARBINOLS CONTAININGAN AMINIC SUBSTITUENT |
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