ANTHRACYCLINE DERIVATIVES HAVING CYTOSTATIC ACTIVITY

of the disclosure The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I wherein R1 is a CH3(CH2)n group with n = 0 to 3, R2 is a hydrogen atom or a methyl group, R3 is a hydrogen atom, a methyl group or an acyl protective group, and R4 is a hydro...

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Bibliographische Detailangaben
Hauptverfasser:	KRAEMER, HANS P, PAAL, MICHAEL, KOLAR, CENEK, HERMENTIN, PETER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
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Beschreibung
Zusammenfassung:	of the disclosure The invention relates to new anthracycline derivatives having cytostatic activity and the general formula I wherein R1 is a CH3(CH2)n group with n = 0 to 3, R2 is a hydrogen atom or a methyl group, R3 is a hydrogen atom, a methyl group or an acyl protective group, and R4 is a hydrogen atom or an acyl protective group, and which are optionally in the form of a salt of an inorganic or organic acid, to a process for their preparation and to their use in pharmaceuticals.