CONTRACEPTIVE VAGINAL TABLETS AND PROCESS FOR PREPARING THEM

The invention relates to contraceptive vaginal tablets and to a process for preparing them. The tablets of the invention have the following composition: 0.2 to 3 parts by weight of boric acid, 10 to 20 parts by weight of tartaric acid, 1 to 2 parts by weight of vitamin K3sodium bisulfite adduct, 0.8...

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Hauptverfasser: SZEBENI, RUDOLF, KOVACS, ANDRAS, KOESZEGI, BELA
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creator SZEBENI, RUDOLF
KOVACS, ANDRAS
KOESZEGI, BELA
description The invention relates to contraceptive vaginal tablets and to a process for preparing them. The tablets of the invention have the following composition: 0.2 to 3 parts by weight of boric acid, 10 to 20 parts by weight of tartaric acid, 1 to 2 parts by weight of vitamin K3sodium bisulfite adduct, 0.8 to 1.2 parts by weight of polyvinyl pyrrolidone, 2 to 5 parts by weight of magnesium stearate, 8 to 12 parts by weight of carboxymethyl cellulose, 8 to 12 parts by weight of lactose and 50 to 65 parts by weight of microcrystalline cellulose. The vaginal tablets contain preferably 5 to 10 mg of vitamin K3-sodium bisulfite adduct and have a total weight of 500 mg. The tablets are prepared preferably in such a way that the boric acid, the tartaric acid and the vitamin K3-sodium bisulfite adduct, as well as the polyvinyl pyrrolidone, the magnesium stearate, the carboxymethyl cellulose, the lactose and the microcrystalline cellulose are homogenized separately to powder mixtures and thereafter the powder mixtures are mixed and pressed to form tablets. The tablets should be wetted and inserted into the back-vaginal fornix 10 minutes before the coitus.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title CONTRACEPTIVE VAGINAL TABLETS AND PROCESS FOR PREPARING THEM
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