PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN
PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN This invention relates to crosslinked collagen and glycosaminoglycan materials, and to procedures for preparing such materials. It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted...
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| creator | FORBES, MARTIN J YANNAS, IOANNIS V |
| description | PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN This invention relates to crosslinked collagen and glycosaminoglycan materials, and to procedures for preparing such materials. It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted with a crosslinking agent before being contacted with glycosaminoglycan, the materials produced have extremely low levels of thrombogenicity. Such materials are well suited for in-dwelling catheters, blood vessel grafts, and other devices that are in continuous contact with blood for long periods of time. |
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It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted with a crosslinking agent before being contacted with glycosaminoglycan, the materials produced have extremely low levels of thrombogenicity. Such materials are well suited for in-dwelling catheters, blood vessel grafts, and other devices that are in continuous contact with blood for long periods of time.</description><edition>4</edition><language>eng ; fre</language><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS ; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; CHEMISTRY ; COMPOSITIONS BASED THEREON ; COMPOSITIONS OF MACROMOLECULAR COMPOUNDS ; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. 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It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted with a crosslinking agent before being contacted with glycosaminoglycan, the materials produced have extremely low levels of thrombogenicity. Such materials are well suited for in-dwelling catheters, blood vessel grafts, and other devices that are in continuous contact with blood for long periods of time.</description><subject>BANDAGES, DRESSINGS OR ABSORBENT PADS</subject><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS BASED THEREON</subject><subject>COMPOSITIONS OF MACROMOLECULAR COMPOUNDS</subject><subject>DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. 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STENTS</topic><topic>DISINFECTION, STERILISATION, OR DEODORISATION OF AIR</topic><topic>FILTERS IMPLANTABLE INTO BLOOD VESSELS</topic><topic>FIRST-AID KITS</topic><topic>FOMENTATION</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</topic><topic>ORGANIC MACROMOLECULAR COMPOUNDS</topic><topic>ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES</topic><topic>PROSTHESES</topic><topic>THEIR PREPARATION OR CHEMICAL WORKING-UP</topic><topic>TREATMENT OR PROTECTION OF EYES OR EARS</topic><toplevel>online_resources</toplevel><creatorcontrib>FORBES, MARTIN J</creatorcontrib><creatorcontrib>YANNAS, IOANNIS V</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FORBES, MARTIN J</au><au>YANNAS, IOANNIS V</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN</title><date>1985-11-26</date><risdate>1985</risdate><abstract>PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN This invention relates to crosslinked collagen and glycosaminoglycan materials, and to procedures for preparing such materials. It has been discovered that if collagen fibrils in an aqueous acidic solution are contacted with a crosslinking agent before being contacted with glycosaminoglycan, the materials produced have extremely low levels of thrombogenicity. Such materials are well suited for in-dwelling catheters, blood vessel grafts, and other devices that are in continuous contact with blood for long periods of time.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre |
| recordid | cdi_epo_espacenet_CA1197189A |
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| subjects | BANDAGES, DRESSINGS OR ABSORBENT PADS CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS OF MACROMOLECULAR COMPOUNDS DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS DISINFECTION, STERILISATION, OR DEODORISATION OF AIR FILTERS IMPLANTABLE INTO BLOOD VESSELS FIRST-AID KITS FOMENTATION HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METALLURGY METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL ORGANIC MACROMOLECULAR COMPOUNDS ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES PROSTHESES THEIR PREPARATION OR CHEMICAL WORKING-UP TREATMENT OR PROTECTION OF EYES OR EARS |
| title | PROCEDURES FOR PREPARING COMPOSITE MATERIALS FROM COLLAGEN AND GLYCOSAMINOGLYCAN |
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