TRI-IODATED ISOPHTHALIC ACID DIAMIDES AS NON-IONIC X-RAY CONTRAST AGENTS

The invention provides compounds of the general formula (I) in which The amide radicals -CO-NR1R2 and -CO-NR3R4 are different from one another, and R1 represents a hydrogen atom or a lower alkyl radical, R2 represents a mono- or poly-hydroxyalkyl radical, R3 represents a hydrogen atom or a lower alk...

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Hauptverfasser: BLASZKIEWICZ, PETER, KLIEGER, ERICH, SPECK, ULRICH, SEIDELMANN, DIETER
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creator BLASZKIEWICZ, PETER
KLIEGER, ERICH
SPECK, ULRICH
SEIDELMANN, DIETER
description The invention provides compounds of the general formula (I) in which The amide radicals -CO-NR1R2 and -CO-NR3R4 are different from one another, and R1 represents a hydrogen atom or a lower alkyl radical, R2 represents a mono- or poly-hydroxyalkyl radical, R3 represents a hydrogen atom or a lower alkyl radical, R4 represents a mono- or poly-hydroxyalkyl radical, R5 represents a lower alkyl radical or a lower alkyl radical substituted by 1 or more of the same or different substituents selected from hydroxy groups and lower alkoxy radicals, R6 represents a hydrogen atom, a lower alkyl radical or a mono- or poly-hydroxy-lower alkyl radical, useful as X-ray contrast agents, especially for intravascular, subarachnoidal and local application.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title TRI-IODATED ISOPHTHALIC ACID DIAMIDES AS NON-IONIC X-RAY CONTRAST AGENTS
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