CYCLODODECANE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF

The invention relates to novel cyclododecane derivatives of the general formula (I), wherein R1 and R2 represent independently from each other a hydrogen atom, a C1-6 alkyl group or a C3-8 cycloalkyl group, or R1 and R2 form together with the nitrogen atom to which they are attached a heterocyclic r...

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Hauptverfasser: KOSOCZKY, IBOLYA, PETOECZ, LUJZA, GRASSER, KATALIN, KISZELLY, ENIKOE, BUDAI, ZOLTAN, MEZEI, TIBOR, LAY, ARANKA (NEE KONYA)
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creator KOSOCZKY, IBOLYA
PETOECZ, LUJZA
GRASSER, KATALIN
KISZELLY, ENIKOE
BUDAI, ZOLTAN
MEZEI, TIBOR
LAY, ARANKA (NEE KONYA)
description The invention relates to novel cyclododecane derivatives of the general formula (I), wherein R1 and R2 represent independently from each other a hydrogen atom, a C1-6 alkyl group or a C3-8 cycloalkyl group, or R1 and R2 form together with the nitrogen atom to which they are attached a heterocyclic ring containing 4 to 7 carbon atoms and optionally a further heteroatom selected from the group consisting of oxygen, sulphur and nitrogen, said ring may be optionally substituted by a C1-3 alkyl or benxyl group; and A represents a C2-6 straight or branched alkylene chain, and optionally active isomers, acid addition salts and quaternary ammonium derivatives thereof. The invention relates further to an analogous process for the preparation of said compounds, to pharmaceutical compoitions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions. The cyclododecane derovatives of the invention possess valuable biological properties.
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The invention relates further to an analogous process for the preparation of said compounds, to pharmaceutical compoitions containing said compounds as the active ingredient and to a process for the preparation of said pharmaceutical compositions. 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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title CYCLODODECANE DERIVATIVES AND A PROCESS FOR THE PREPARATION THEREOF
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