derivados de triazinona substituída
A triazinone derivative represented by formula (I) wherein: wherein: Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen...
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| creator | PHILIPPE YAICHE ALISTAIR LOCHEAD MOURAD SAADY |
| description | A triazinone derivative represented by formula (I)
wherein:
wherein:
Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen atom, a C 1-6 alkyl; R3 represents a hydrogen atom, a C 1-6 alkyl group; R2 and R3 may form together a 6 membered cycle with the nitrogens caring R2 and R3 optionally substituted; R4 represents: a phenyl ring, being optionally substituted; n represents 0 to 2; in form of a free base or of an addition salt with an acid.
These compounds are useful as GSK3-² inhibitors. |
| format | Patent |
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wherein:
wherein:
Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen atom, a C 1-6 alkyl; R3 represents a hydrogen atom, a C 1-6 alkyl group; R2 and R3 may form together a 6 membered cycle with the nitrogens caring R2 and R3 optionally substituted; R4 represents: a phenyl ring, being optionally substituted; n represents 0 to 2; in form of a free base or of an addition salt with an acid.
These compounds are useful as GSK3-² inhibitors.</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151020&DB=EPODOC&CC=BR&NR=PI0914662A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151020&DB=EPODOC&CC=BR&NR=PI0914662A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PHILIPPE YAICHE</creatorcontrib><creatorcontrib>ALISTAIR LOCHEAD</creatorcontrib><creatorcontrib>MOURAD SAADY</creatorcontrib><title>derivados de triazinona substituída</title><description>A triazinone derivative represented by formula (I)
wherein:
wherein:
Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen atom, a C 1-6 alkyl; R3 represents a hydrogen atom, a C 1-6 alkyl group; R2 and R3 may form together a 6 membered cycle with the nitrogens caring R2 and R3 optionally substituted; R4 represents: a phenyl ring, being optionally substituted; n represents 0 to 2; in form of a free base or of an addition salt with an acid.
These compounds are useful as GSK3-² inhibitors.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFBJSS3KLEtMyS9WSElVKCnKTKzKzMvPS1QoLk0qLsksKT28NiWRh4E1LTGnOJUXSnMzKLm5hjh76KYW5MenFhckJqfmpZbEOwUFeBpYGpqYmRk5GhkTpQgA2M8owg</recordid><startdate>20151020</startdate><enddate>20151020</enddate><creator>PHILIPPE YAICHE</creator><creator>ALISTAIR LOCHEAD</creator><creator>MOURAD SAADY</creator><scope>EVB</scope></search><sort><creationdate>20151020</creationdate><title>derivados de triazinona substituída</title><author>PHILIPPE YAICHE ; ALISTAIR LOCHEAD ; MOURAD SAADY</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0914662A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>PHILIPPE YAICHE</creatorcontrib><creatorcontrib>ALISTAIR LOCHEAD</creatorcontrib><creatorcontrib>MOURAD SAADY</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PHILIPPE YAICHE</au><au>ALISTAIR LOCHEAD</au><au>MOURAD SAADY</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>derivados de triazinona substituída</title><date>2015-10-20</date><risdate>2015</risdate><abstract>A triazinone derivative represented by formula (I)
wherein:
wherein:
Z represents a bond, a carbonyl group, a methylene group optionally substituted by one or two groups chosen from a C 1-6 alkyl group, a hydroxyl group, a C 1-6 alkoxy group; R1 represents a 4-pyridine ring; R2 represents a hydrogen atom, a C 1-6 alkyl; R3 represents a hydrogen atom, a C 1-6 alkyl group; R2 and R3 may form together a 6 membered cycle with the nitrogens caring R2 and R3 optionally substituted; R4 represents: a phenyl ring, being optionally substituted; n represents 0 to 2; in form of a free base or of an addition salt with an acid.
These compounds are useful as GSK3-² inhibitors.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | derivados de triazinona substituída |
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