composto de 5-hidroxipirimidina-4-carboxamida
The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided: [wherein, R 1 represents a group -X-Q 1 , X-Q 1 -Y-Q 2 or -X-Q 1 -Y-Q 2 -Z-Q 3 , X represents a sin...
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| creator | RIEKO TAKANO TAKASHI TSUJI NAOKI TANAKA TAKESHI KURIBAYASHI TAKESHI FUKUDA KOJI SASAKI HIDEKI KUBOTA |
| description | The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided:
[wherein, R 1 represents a group -X-Q 1 , X-Q 1 -Y-Q 2 or -X-Q 1 -Y-Q 2 -Z-Q 3 , X represents a single bond, -CH 2 - or the like, Q 1 represents a monocyclic or bicyclic heterocyclic group which may have substituent(s), Y represents a single bond, -CH 2 -, or the like, Q 2 represents a monocyclic or bicyclic hydrocarbon ring group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), Z represents a single bond, -CR 11 R 12 - or the like, R 11 and R 12 each independently represents a hydrogen atom, a halogen atom or the like, Q 3 represents a phenyl group which may have substituent(s), a C 3 -C 7 cycloalkyl group which may have substituent(s), a C 3 -C 7 cycloalkenyl group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), R 2 represents a C 1 -C 3 alkyl group or the like, and R 3 represents a hydrogen atom or a methyl group]. |
| format | Patent |
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[wherein, R 1 represents a group -X-Q 1 , X-Q 1 -Y-Q 2 or -X-Q 1 -Y-Q 2 -Z-Q 3 , X represents a single bond, -CH 2 - or the like, Q 1 represents a monocyclic or bicyclic heterocyclic group which may have substituent(s), Y represents a single bond, -CH 2 -, or the like, Q 2 represents a monocyclic or bicyclic hydrocarbon ring group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), Z represents a single bond, -CR 11 R 12 - or the like, R 11 and R 12 each independently represents a hydrogen atom, a halogen atom or the like, Q 3 represents a phenyl group which may have substituent(s), a C 3 -C 7 cycloalkyl group which may have substituent(s), a C 3 -C 7 cycloalkenyl group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), R 2 represents a C 1 -C 3 alkyl group or the like, and R 3 represents a hydrogen atom or a methyl group].</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2015</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151229&DB=EPODOC&CC=BR&NR=PI0911393A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,782,887,25573,76557</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20151229&DB=EPODOC&CC=BR&NR=PI0911393A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RIEKO TAKANO</creatorcontrib><creatorcontrib>TAKASHI TSUJI</creatorcontrib><creatorcontrib>NAOKI TANAKA</creatorcontrib><creatorcontrib>TAKESHI KURIBAYASHI</creatorcontrib><creatorcontrib>TAKESHI FUKUDA</creatorcontrib><creatorcontrib>KOJI SASAKI</creatorcontrib><creatorcontrib>HIDEKI KUBOTA</creatorcontrib><title>composto de 5-hidroxipirimidina-4-carboxamida</title><description>The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided:
[wherein, R 1 represents a group -X-Q 1 , X-Q 1 -Y-Q 2 or -X-Q 1 -Y-Q 2 -Z-Q 3 , X represents a single bond, -CH 2 - or the like, Q 1 represents a monocyclic or bicyclic heterocyclic group which may have substituent(s), Y represents a single bond, -CH 2 -, or the like, Q 2 represents a monocyclic or bicyclic hydrocarbon ring group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), Z represents a single bond, -CR 11 R 12 - or the like, R 11 and R 12 each independently represents a hydrogen atom, a halogen atom or the like, Q 3 represents a phenyl group which may have substituent(s), a C 3 -C 7 cycloalkyl group which may have substituent(s), a C 3 -C 7 cycloalkenyl group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), R 2 represents a C 1 -C 3 alkyl group or the like, and R 3 represents a hydrogen atom or a methyl group].</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2015</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBNzs8tyC8uyVdISVUw1c3ITCnKr8gsyCzKzM1MycxL1DXRTU4sSsqvSATyE3kYWNMSc4pTeaE0N4OSm2uIs4duakF-fGpxQWJyal5qSbxTUICngaWhobGlsaORMVGKAB84Kus</recordid><startdate>20151229</startdate><enddate>20151229</enddate><creator>RIEKO TAKANO</creator><creator>TAKASHI TSUJI</creator><creator>NAOKI TANAKA</creator><creator>TAKESHI KURIBAYASHI</creator><creator>TAKESHI FUKUDA</creator><creator>KOJI SASAKI</creator><creator>HIDEKI KUBOTA</creator><scope>EVB</scope></search><sort><creationdate>20151229</creationdate><title>composto de 5-hidroxipirimidina-4-carboxamida</title><author>RIEKO TAKANO ; TAKASHI TSUJI ; NAOKI TANAKA ; TAKESHI KURIBAYASHI ; TAKESHI FUKUDA ; KOJI SASAKI ; HIDEKI KUBOTA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0911393A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2015</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>RIEKO TAKANO</creatorcontrib><creatorcontrib>TAKASHI TSUJI</creatorcontrib><creatorcontrib>NAOKI TANAKA</creatorcontrib><creatorcontrib>TAKESHI KURIBAYASHI</creatorcontrib><creatorcontrib>TAKESHI FUKUDA</creatorcontrib><creatorcontrib>KOJI SASAKI</creatorcontrib><creatorcontrib>HIDEKI KUBOTA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RIEKO TAKANO</au><au>TAKASHI TSUJI</au><au>NAOKI TANAKA</au><au>TAKESHI KURIBAYASHI</au><au>TAKESHI FUKUDA</au><au>KOJI SASAKI</au><au>HIDEKI KUBOTA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>composto de 5-hidroxipirimidina-4-carboxamida</title><date>2015-12-29</date><risdate>2015</risdate><abstract>The present invention provides compounds which promote erythropoietin production. Compounds represented by the following general formula (1) or pharmacologically acceptable salts thereof are provided:
[wherein, R 1 represents a group -X-Q 1 , X-Q 1 -Y-Q 2 or -X-Q 1 -Y-Q 2 -Z-Q 3 , X represents a single bond, -CH 2 - or the like, Q 1 represents a monocyclic or bicyclic heterocyclic group which may have substituent(s), Y represents a single bond, -CH 2 -, or the like, Q 2 represents a monocyclic or bicyclic hydrocarbon ring group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), Z represents a single bond, -CR 11 R 12 - or the like, R 11 and R 12 each independently represents a hydrogen atom, a halogen atom or the like, Q 3 represents a phenyl group which may have substituent(s), a C 3 -C 7 cycloalkyl group which may have substituent(s), a C 3 -C 7 cycloalkenyl group which may have substituent(s) or a monocyclic or bicyclic heterocyclic group which may have substituent(s), R 2 represents a C 1 -C 3 alkyl group or the like, and R 3 represents a hydrogen atom or a methyl group].</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | composto de 5-hidroxipirimidina-4-carboxamida |
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