PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS

The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C( O)-OR1a, -C( O)-NR1bR1c, -C( O)-SR1d or -C( S)-SR1e; R2...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: THOMAS GROTE, JOCHEN DIETZ, JAN KLASS LOHMANN, SEBASTIAN PEER SMIDT, MARKUS NETT, MICHAEL RACK, THOMAS ZIERKE
Format: Patent
Sprache:por
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator THOMAS GROTE
JOCHEN DIETZ
JAN KLASS LOHMANN
SEBASTIAN PEER SMIDT
MARKUS NETT
MICHAEL RACK
THOMAS ZIERKE
description The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C( O)-OR1a, -C( O)-NR1bR1c, -C( O)-SR1d or -C( S)-SR1e; R2 is H, C1-C4-alkyl, benzyl or phenyl; R3 is H, halogen, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkoxy, C2-C8-alkenyloxy, C1-C8-alkylthio, C1-C8-haloalkylthio, C3-C8-cyclo-alkylthio or C2-C8-alkenylthio; compounds of the formula (II.a) or (II.b), in which R1 and R3 each have one of the definitions given above; R4 is halogen, -OR4a, -SR4a, -O-SO2-R4a or an -NR4bR4c group; R5 and R6 are each C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI); and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_BRPI0812958A2</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>BRPI0812958A2</sourcerecordid><originalsourceid>FETCH-epo_espacenet_BRPI0812958A23</originalsourceid><addsrcrecordid>eNrjZHAICPJ3dg0O9lcIcAxyVAgIcgXRQQrO_r4B_sEh_sE6CqFASRdXZBFXHQSPh4E1LTGnOJUXSnMzKLm5hjh76KYW5MenFhckJqfmpZbEOwUFeBpYGBpZmlo4GhkTpQgAFmgrlA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS</title><source>esp@cenet</source><creator>THOMAS GROTE ; JOCHEN DIETZ ; JAN KLASS LOHMANN ; SEBASTIAN PEER SMIDT ; MARKUS NETT ; MICHAEL RACK ; THOMAS ZIERKE</creator><creatorcontrib>THOMAS GROTE ; JOCHEN DIETZ ; JAN KLASS LOHMANN ; SEBASTIAN PEER SMIDT ; MARKUS NETT ; MICHAEL RACK ; THOMAS ZIERKE</creatorcontrib><description>The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C( O)-OR1a, -C( O)-NR1bR1c, -C( O)-SR1d or -C( S)-SR1e; R2 is H, C1-C4-alkyl, benzyl or phenyl; R3 is H, halogen, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkoxy, C2-C8-alkenyloxy, C1-C8-alkylthio, C1-C8-haloalkylthio, C3-C8-cyclo-alkylthio or C2-C8-alkenylthio; compounds of the formula (II.a) or (II.b), in which R1 and R3 each have one of the definitions given above; R4 is halogen, -OR4a, -SR4a, -O-SO2-R4a or an -NR4bR4c group; R5 and R6 are each C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI); and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; METALLURGY ; ORGANIC CHEMISTRY</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20141209&amp;DB=EPODOC&amp;CC=BR&amp;NR=PI0812958A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20141209&amp;DB=EPODOC&amp;CC=BR&amp;NR=PI0812958A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>THOMAS GROTE</creatorcontrib><creatorcontrib>JOCHEN DIETZ</creatorcontrib><creatorcontrib>JAN KLASS LOHMANN</creatorcontrib><creatorcontrib>SEBASTIAN PEER SMIDT</creatorcontrib><creatorcontrib>MARKUS NETT</creatorcontrib><creatorcontrib>MICHAEL RACK</creatorcontrib><creatorcontrib>THOMAS ZIERKE</creatorcontrib><title>PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS</title><description>The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C( O)-OR1a, -C( O)-NR1bR1c, -C( O)-SR1d or -C( S)-SR1e; R2 is H, C1-C4-alkyl, benzyl or phenyl; R3 is H, halogen, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkoxy, C2-C8-alkenyloxy, C1-C8-alkylthio, C1-C8-haloalkylthio, C3-C8-cyclo-alkylthio or C2-C8-alkenylthio; compounds of the formula (II.a) or (II.b), in which R1 and R3 each have one of the definitions given above; R4 is halogen, -OR4a, -SR4a, -O-SO2-R4a or an -NR4bR4c group; R5 and R6 are each C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI); and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAICPJ3dg0O9lcIcAxyVAgIcgXRQQrO_r4B_sEh_sE6CqFASRdXZBFXHQSPh4E1LTGnOJUXSnMzKLm5hjh76KYW5MenFhckJqfmpZbEOwUFeBpYGBpZmlo4GhkTpQgAFmgrlA</recordid><startdate>20141209</startdate><enddate>20141209</enddate><creator>THOMAS GROTE</creator><creator>JOCHEN DIETZ</creator><creator>JAN KLASS LOHMANN</creator><creator>SEBASTIAN PEER SMIDT</creator><creator>MARKUS NETT</creator><creator>MICHAEL RACK</creator><creator>THOMAS ZIERKE</creator><scope>EVB</scope></search><sort><creationdate>20141209</creationdate><title>PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS</title><author>THOMAS GROTE ; JOCHEN DIETZ ; JAN KLASS LOHMANN ; SEBASTIAN PEER SMIDT ; MARKUS NETT ; MICHAEL RACK ; THOMAS ZIERKE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0812958A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2014</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><toplevel>online_resources</toplevel><creatorcontrib>THOMAS GROTE</creatorcontrib><creatorcontrib>JOCHEN DIETZ</creatorcontrib><creatorcontrib>JAN KLASS LOHMANN</creatorcontrib><creatorcontrib>SEBASTIAN PEER SMIDT</creatorcontrib><creatorcontrib>MARKUS NETT</creatorcontrib><creatorcontrib>MICHAEL RACK</creatorcontrib><creatorcontrib>THOMAS ZIERKE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>THOMAS GROTE</au><au>JOCHEN DIETZ</au><au>JAN KLASS LOHMANN</au><au>SEBASTIAN PEER SMIDT</au><au>MARKUS NETT</au><au>MICHAEL RACK</au><au>THOMAS ZIERKE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS</title><date>2014-12-09</date><risdate>2014</risdate><abstract>The present invention relates to a process for preparing 3-difluoromethyl-Substituted pyrazole compounds of the formula (I) in which R1 is H, halogen, nitro, C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, phenyl, naphthyl, hetaryl, cyano, -C( O)-OR1a, -C( O)-NR1bR1c, -C( O)-SR1d or -C( S)-SR1e; R2 is H, C1-C4-alkyl, benzyl or phenyl; R3 is H, halogen, C1-C8-alkoxy, C1-C8-haloalkoxy, C3-C8-cycloalkoxy, C2-C8-alkenyloxy, C1-C8-alkylthio, C1-C8-haloalkylthio, C3-C8-cyclo-alkylthio or C2-C8-alkenylthio; compounds of the formula (II.a) or (II.b), in which R1 and R3 each have one of the definitions given above; R4 is halogen, -OR4a, -SR4a, -O-SO2-R4a or an -NR4bR4c group; R5 and R6 are each C1-C8-alkyl, C1-C8-haloalkyl, C3-C8-cycloalkyl, benzyl or phenyl, or, together with the nitrogen atom to which they are bonded, are a 3- to 8-membered heterocycle; Lewis acid adducts of compounds of the formula (II.b); the use of compounds of the formula (II.a) or (II.b) and of the Lewis acid adducts for preparing compounds of the formula (I) or (VI); and to a process for converting such compounds to the corresponding 3-difluoro-pyrazol-4-ylcarboxylic acids.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language por
recordid cdi_epo_espacenet_BRPI0812958A2
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESSO PARA PREPARAR COMPOSTOS, USO DE COMPOSTOS, E, COMPOSTOS
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-03T01%3A10%3A38IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=THOMAS%20GROTE&rft.date=2014-12-09&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EBRPI0812958A2%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true