SAIS MONOCLORÍDRICOS DE UM INIBIDOR DE HISTONA DESACETILASE

This invention provides novel crystalline forms of mono-HCl salts and a mono-HCl salt hydrate of JNJ-26481585, an inhibitor of histone deacetylases. The invention also relates to processes for production of these forms, to intermediates used in these processes, to pharmaceutical compositions compris...

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Hauptverfasser: JULIUS W.J. DICKENS, CARINA LEYS, SIGRID CARL MARIA STOKBROEKX, YOLANDE LYDIA LANG, IOANNES NICOLAOS HOUPIS, JOHAN ERWIN EDMOND WEERTS
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creator JULIUS W.J. DICKENS
CARINA LEYS
SIGRID CARL MARIA STOKBROEKX
YOLANDE LYDIA LANG
IOANNES NICOLAOS HOUPIS
JOHAN ERWIN EDMOND WEERTS
description This invention provides novel crystalline forms of mono-HCl salts and a mono-HCl salt hydrate of JNJ-26481585, an inhibitor of histone deacetylases. The invention also relates to processes for production of these forms, to intermediates used in these processes, to pharmaceutical compositions comprising these forms, and to the use of these forms in medical treatment for instance as a medicine to inhibit proliferative conditions, such as cancer and leukemia.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title SAIS MONOCLORÍDRICOS DE UM INIBIDOR DE HISTONA DESACETILASE
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