FORMULAÇÃO DE NICOTINA ORAL TAMPONADA COM AMINOÁCIDO

A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least one amino acid, preferably at least one endogenous amino acid. Also contemplated is a...

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Hauptverfasser: FREDRIK NICKLASSON, ROLAND OLSSON, GUNNAR BERGENGREN, SVEN-BOERJE ANDERSSON, BENGT BOSSON, ANDREAS HUGERTH
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creator FREDRIK NICKLASSON
ROLAND OLSSON
GUNNAR BERGENGREN
SVEN-BOERJE ANDERSSON
BENGT BOSSON
ANDREAS HUGERTH
description A pharmaceutical oral formulation for delivering nicotine in any form to a subject by transmucosal uptake in the oral cavity comprising nicotine in any form, wherein said oral formulation is buffered with at least one amino acid, preferably at least one endogenous amino acid. Also contemplated is a method for the oral delivery of nicotine in any form, a method for the reduction of the urge to smoke or use tobacco as well as methods for manufacturing the oral formulation, the use of said oral formulation for obtaining transmucosal uptake of nicotine in the oral cavity of a subject, and use of nicotine for the production of an oral formulation as per above for the treatment of a disease selected from the group consisting of tobacco or nicotine dependence, Alzheimer's disease, Crohn's disease, Parkinson's disease, Tourette's syndrome, ulcerous colitis and post-smoking-cessation weight control.
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recordid cdi_epo_espacenet_BRPI0811110A2
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subjects CIGARETTES
CIGARS
HUMAN NECESSITIES
HYGIENE
MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING ORCHEWING
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SMOKERS' REQUISITES
SNUFF
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TOBACCO
title FORMULAÇÃO DE NICOTINA ORAL TAMPONADA COM AMINOÁCIDO
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