Processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico
processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico. a invenção refere-se a um processo para a preparação de um composto de fórmula (i): (i) r1 é selecionado de c1-6alquila, c2-6alquenila, e c2-6alquinila; que compreende: (i) reação com...
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| creator | Langstrom Bengt Clare Louise Jones Williams Lorenzo Lasbistes Nicolas Anthony Eamonn Storey Karimi Farhad Robert James Nairne Denis Raymond Christople Bouvet Steven Michael Fairway Alexandre Mark Gibson |
| description | processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico. a invenção refere-se a um processo para a preparação de um composto de fórmula (i): (i) r1 é selecionado de c1-6alquila, c2-6alquenila, e c2-6alquinila; que compreende: (i) reação com fluoreto, adequadamente fluoreto [18f], de um correspondente composto de fórmula (ii): (ii) na qual r2 é selecionado de hidrogênio, c1-10alquila, c1-10halo-alquila, c6-14arila, c6-14aril-alquila, -(ch2ch2o)q-ch3 na qual q é um número inteiro de 1 a 10; r1 é como definido para o composto de fórmula (i); e r3 é um grupo de saída. certos novos precursores de fórmula (ii) e kits radiofarmacêuticos contendo tais precursores também são reivindicados.
The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl; which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, -(CH2CH2O)q-CH3 wherein q is an integer of from 1 to 10; R1 is as defined for the compound of formula (I); and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed. |
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The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl; which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, -(CH2CH2O)q-CH3 wherein q is an integer of from 1 to 10; R1 is as defined for the compound of formula (I); and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.</description><language>por</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; NUCLEAR ENGINEERING ; NUCLEAR PHYSICS ; NUCLEAR REACTORS ; ORGANIC CHEMISTRY ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240109&DB=EPODOC&CC=BR&NR=PI0614752B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240109&DB=EPODOC&CC=BR&NR=PI0614752B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Langstrom Bengt</creatorcontrib><creatorcontrib>Clare Louise Jones</creatorcontrib><creatorcontrib>Williams Lorenzo</creatorcontrib><creatorcontrib>Lasbistes Nicolas</creatorcontrib><creatorcontrib>Anthony Eamonn Storey</creatorcontrib><creatorcontrib>Karimi Farhad</creatorcontrib><creatorcontrib>Robert James Nairne</creatorcontrib><creatorcontrib>Denis Raymond Christople Bouvet</creatorcontrib><creatorcontrib>Steven Michael Fairway</creatorcontrib><creatorcontrib>Alexandre Mark Gibson</creatorcontrib><title>Processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico</title><description>processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico. a invenção refere-se a um processo para a preparação de um composto de fórmula (i): (i) r1 é selecionado de c1-6alquila, c2-6alquenila, e c2-6alquinila; que compreende: (i) reação com fluoreto, adequadamente fluoreto [18f], de um correspondente composto de fórmula (ii): (ii) na qual r2 é selecionado de hidrogênio, c1-10alquila, c1-10halo-alquila, c6-14arila, c6-14aril-alquila, -(ch2ch2o)q-ch3 na qual q é um número inteiro de 1 a 10; r1 é como definido para o composto de fórmula (i); e r3 é um grupo de saída. certos novos precursores de fórmula (ii) e kits radiofarmacêuticos contendo tais precursores também são reivindicados.
The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl; which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, -(CH2CH2O)q-CH3 wherein q is an integer of from 1 to 10; R1 is as defined for the compound of formula (I); and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEAR ENGINEERING</subject><subject>NUCLEAR PHYSICS</subject><subject>NUCLEAR REACTORS</subject><subject>ORGANIC CHEMISTRY</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZCgPKMpPTi0uzlcoSCxKVCgoSgXRh5cfXpyvkJKqUJqrkJyfW5BfXJKvg8TKzixRKEpMycxPSyzKTUw-vKq0JDMZKJ4KVJRYVFKanAE1D6gfu1oeBta0xJziVF4ozc2g5OYa4uyhm1qQH59aXJCYnJqXWhLvFBTgaWBmaGJuauRkaEyUIgB2RUk1</recordid><startdate>20240109</startdate><enddate>20240109</enddate><creator>Langstrom Bengt</creator><creator>Clare Louise Jones</creator><creator>Williams Lorenzo</creator><creator>Lasbistes Nicolas</creator><creator>Anthony Eamonn Storey</creator><creator>Karimi Farhad</creator><creator>Robert James Nairne</creator><creator>Denis Raymond Christople Bouvet</creator><creator>Steven Michael Fairway</creator><creator>Alexandre Mark Gibson</creator><scope>EVB</scope></search><sort><creationdate>20240109</creationdate><title>Processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico</title><author>Langstrom Bengt ; Clare Louise Jones ; Williams Lorenzo ; Lasbistes Nicolas ; Anthony Eamonn Storey ; Karimi Farhad ; Robert James Nairne ; Denis Raymond Christople Bouvet ; Steven Michael Fairway ; Alexandre Mark Gibson</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0614752B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2024</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEAR ENGINEERING</topic><topic>NUCLEAR PHYSICS</topic><topic>NUCLEAR REACTORS</topic><topic>ORGANIC CHEMISTRY</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>Langstrom Bengt</creatorcontrib><creatorcontrib>Clare Louise Jones</creatorcontrib><creatorcontrib>Williams Lorenzo</creatorcontrib><creatorcontrib>Lasbistes Nicolas</creatorcontrib><creatorcontrib>Anthony Eamonn Storey</creatorcontrib><creatorcontrib>Karimi Farhad</creatorcontrib><creatorcontrib>Robert James Nairne</creatorcontrib><creatorcontrib>Denis Raymond Christople Bouvet</creatorcontrib><creatorcontrib>Steven Michael Fairway</creatorcontrib><creatorcontrib>Alexandre Mark Gibson</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Langstrom Bengt</au><au>Clare Louise Jones</au><au>Williams Lorenzo</au><au>Lasbistes Nicolas</au><au>Anthony Eamonn Storey</au><au>Karimi Farhad</au><au>Robert James Nairne</au><au>Denis Raymond Christople Bouvet</au><au>Steven Michael Fairway</au><au>Alexandre Mark Gibson</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico</title><date>2024-01-09</date><risdate>2024</risdate><abstract>processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico. a invenção refere-se a um processo para a preparação de um composto de fórmula (i): (i) r1 é selecionado de c1-6alquila, c2-6alquenila, e c2-6alquinila; que compreende: (i) reação com fluoreto, adequadamente fluoreto [18f], de um correspondente composto de fórmula (ii): (ii) na qual r2 é selecionado de hidrogênio, c1-10alquila, c1-10halo-alquila, c6-14arila, c6-14aril-alquila, -(ch2ch2o)q-ch3 na qual q é um número inteiro de 1 a 10; r1 é como definido para o composto de fórmula (i); e r3 é um grupo de saída. certos novos precursores de fórmula (ii) e kits radiofarmacêuticos contendo tais precursores também são reivindicados.
The invention relates to a process for preparation of a compound of formula (I): R1 is selected from C1-6alkyl, C2-6alkenyl, and C2-6alkynyl; which comprises: (i) reaction with fluoride, suitably [18F]fluoride, of a corresponding compound of formula (II): wherein R2 is selected from hydrogen, C1-10alkyl, C1-10haloalkyl, C6-14aryl, C6-14arylalkyl, -(CH2CH2O)q-CH3 wherein q is an integer of from 1 to 10; R1 is as defined for the compound of formula (I); and R3 is a leaving group. Certain novel precursors of formula (II) and radiopharmaceutical kits containing such precursors are also claimed.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEAR ENGINEERING NUCLEAR PHYSICS NUCLEAR REACTORS ORGANIC CHEMISTRY PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | Processo para preparação de um composto, composto, kit radiofarmacêutico, e, cartucho para um kit radiofarmacêutico |
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