anticorpos antil-il-13 e complexos

ANTICORPOS ANTI-IL-13 E COMPLEXOS. A presente invenção refere-se a Anticorposanti-IL-13, cristais de anticorpos anti-IL-13, complexos polipeptídeo IL-13/anticorpo anti-IL-13, cristais de complexos polipeptídeo IL-13/anticorpo anti-IL-13, complexos polipeptídeo IL-13R 1/polipeptídeo IL-13/anticorpo anti-IL-13, cristais de complexos polipeptídeo IL-13R 1/polipeptídeo IL-13/anticorpo anti-IL-13, e métodos e sistemas de software relacionados são descritos. This application relates to antibodies, e.g ., humanized antibodies, and antigen-binding fragments thereof, that bind to interleukin-13 (IL-13), in particular, human IL-13, and their uses in regulating immune responses mediated by IL-13. The antibodies disclosed herein are useful in diagnosing, preventing, and/or treating a subject, e.g., a human patient, one or more IL-13-associated disorders, e.g., respiratory disorders ( e.g., asthma); atopic disorders ( e.g ., allergic rhinitis); inflammatory and/or autoimmune conditions of the skin ( e.g., atopic dermatitis), and gastrointestinal organs ( e.g., inflammatory bowel diseases (IBD)), as well as fibrotic and cancerous disorders.