pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas
pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas. em suas muitas modalidades, a presente invenção fornece uma nova classe de compostos pirazolo[1,5-a]pirimidina como inibidores de cinases dependentes de ciclina, métodos de preparar...
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| creator | Vincent Madison Carmen S. Alvarez Timothy Guzi Vidyadhar M. Paradkar Tin-Yau Chan Ronald J. Doll Michael P. Dwyer Lawrence W. Dillard Vinh D. Tran Douglas Walsh Hobbs Kamil Paruch Jocelyn Rivera Kartik M. Keertikar Alan Mallams Thierry O. Fischmann Zhen Min He Ray Anthony James Haengsoon Park Viyyoor Moopil Girijavallabhan |
| description | pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas. em suas muitas modalidades, a presente invenção fornece uma nova classe de compostos pirazolo[1,5-a]pirimidina como inibidores de cinases dependentes de ciclina, métodos de preparar tais compostos, composições farmacêuticas contendo um ou mais compostos, métodos de preparar formulações farmacêuticas compreendendo um ou mais tais compostos e métodos de tratamento, prevenção, inibição ou melhora de uma ou mais doenças associadas às cdks usando tais compostos ou composições farmacêuticas.
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions. |
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In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.</description><language>por</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210525&DB=EPODOC&CC=BR&NR=PI0314001B8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210525&DB=EPODOC&CC=BR&NR=PI0314001B8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Vincent Madison</creatorcontrib><creatorcontrib>Carmen S. Alvarez</creatorcontrib><creatorcontrib>Timothy Guzi</creatorcontrib><creatorcontrib>Vidyadhar M. Paradkar</creatorcontrib><creatorcontrib>Tin-Yau Chan</creatorcontrib><creatorcontrib>Ronald J. Doll</creatorcontrib><creatorcontrib>Michael P. Dwyer</creatorcontrib><creatorcontrib>Lawrence W. Dillard</creatorcontrib><creatorcontrib>Vinh D. Tran</creatorcontrib><creatorcontrib>Douglas Walsh Hobbs</creatorcontrib><creatorcontrib>Kamil Paruch</creatorcontrib><creatorcontrib>Jocelyn Rivera</creatorcontrib><creatorcontrib>Kartik M. Keertikar</creatorcontrib><creatorcontrib>Alan Mallams</creatorcontrib><creatorcontrib>Thierry O. Fischmann</creatorcontrib><creatorcontrib>Zhen Min He</creatorcontrib><creatorcontrib>Ray Anthony James</creatorcontrib><creatorcontrib>Haengsoon Park</creatorcontrib><creatorcontrib>Viyyoor Moopil Girijavallabhan</creatorcontrib><title>pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas</title><description>pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas. em suas muitas modalidades, a presente invenção fornece uma nova classe de compostos pirazolo[1,5-a]pirimidina como inibidores de cinases dependentes de ciclina, métodos de preparar tais compostos, composições farmacêuticas contendo um ou mais compostos, métodos de preparar formulações farmacêuticas compreendendo um ou mais tais compostos e métodos de tratamento, prevenção, inibição ou melhora de uma ou mais doenças associadas às cdks usando tais compostos ou composições farmacêuticas.
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwkAQRNNYiPoPi72QEAvriKKdiH1Y7zawkLs9biOIv2Mh-Bv5MS_RD7CaYd7MTLN74IgPaSUpO7bsUcGIE2DPV7YSScESmAFQcoG8Jd_RNzRtyoGGRRDl_tU_BRqMDk3_vnVscESRxpUVSO-O1KHOs0mDrdLip7Nsud9dtocVBalJAxry1NXV-XTMy2Kd50W1Kf8qfQDjEknY</recordid><startdate>20210525</startdate><enddate>20210525</enddate><creator>Vincent Madison</creator><creator>Carmen S. Alvarez</creator><creator>Timothy Guzi</creator><creator>Vidyadhar M. Paradkar</creator><creator>Tin-Yau Chan</creator><creator>Ronald J. Doll</creator><creator>Michael P. Dwyer</creator><creator>Lawrence W. Dillard</creator><creator>Vinh D. Tran</creator><creator>Douglas Walsh Hobbs</creator><creator>Kamil Paruch</creator><creator>Jocelyn Rivera</creator><creator>Kartik M. Keertikar</creator><creator>Alan Mallams</creator><creator>Thierry O. Fischmann</creator><creator>Zhen Min He</creator><creator>Ray Anthony James</creator><creator>Haengsoon Park</creator><creator>Viyyoor Moopil Girijavallabhan</creator><scope>EVB</scope></search><sort><creationdate>20210525</creationdate><title>pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas</title><author>Vincent Madison ; Carmen S. Alvarez ; Timothy Guzi ; Vidyadhar M. Paradkar ; Tin-Yau Chan ; Ronald J. Doll ; Michael P. Dwyer ; Lawrence W. Dillard ; Vinh D. 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Alvarez</creatorcontrib><creatorcontrib>Timothy Guzi</creatorcontrib><creatorcontrib>Vidyadhar M. Paradkar</creatorcontrib><creatorcontrib>Tin-Yau Chan</creatorcontrib><creatorcontrib>Ronald J. Doll</creatorcontrib><creatorcontrib>Michael P. Dwyer</creatorcontrib><creatorcontrib>Lawrence W. Dillard</creatorcontrib><creatorcontrib>Vinh D. Tran</creatorcontrib><creatorcontrib>Douglas Walsh Hobbs</creatorcontrib><creatorcontrib>Kamil Paruch</creatorcontrib><creatorcontrib>Jocelyn Rivera</creatorcontrib><creatorcontrib>Kartik M. Keertikar</creatorcontrib><creatorcontrib>Alan Mallams</creatorcontrib><creatorcontrib>Thierry O. Fischmann</creatorcontrib><creatorcontrib>Zhen Min He</creatorcontrib><creatorcontrib>Ray Anthony James</creatorcontrib><creatorcontrib>Haengsoon Park</creatorcontrib><creatorcontrib>Viyyoor Moopil Girijavallabhan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Vincent Madison</au><au>Carmen S. Alvarez</au><au>Timothy Guzi</au><au>Vidyadhar M. Paradkar</au><au>Tin-Yau Chan</au><au>Ronald J. Doll</au><au>Michael P. Dwyer</au><au>Lawrence W. Dillard</au><au>Vinh D. Tran</au><au>Douglas Walsh Hobbs</au><au>Kamil Paruch</au><au>Jocelyn Rivera</au><au>Kartik M. Keertikar</au><au>Alan Mallams</au><au>Thierry O. Fischmann</au><au>Zhen Min He</au><au>Ray Anthony James</au><au>Haengsoon Park</au><au>Viyyoor Moopil Girijavallabhan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas</title><date>2021-05-25</date><risdate>2021</risdate><abstract>pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas. em suas muitas modalidades, a presente invenção fornece uma nova classe de compostos pirazolo[1,5-a]pirimidina como inibidores de cinases dependentes de ciclina, métodos de preparar tais compostos, composições farmacêuticas contendo um ou mais compostos, métodos de preparar formulações farmacêuticas compreendendo um ou mais tais compostos e métodos de tratamento, prevenção, inibição ou melhora de uma ou mais doenças associadas às cdks usando tais compostos ou composições farmacêuticas.
In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | pirazolopirimidinas como inibidores de cinase dependente de ciclina e composição farmacêutica compreendendo as mesmas |
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