preparação farmacêutica, sua aplicação farmacêutica, bem como processo para preparação da mesma

"formulação inalável de uma solução contendo um sal de tiotrópio". a presente invenção refere-se a uma formulação inalável de brometo de tiotrópio ou monoidrato de brometo de tiotrópio livre de propelentes dissolvida em água ou em uma mistura de água e etanol e aos aerossóis inaláveis livr...

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Hauptverfasser: BARBARA NIKLAUS-HUMKE, PETRA BARTH, CHRISTEL SCHMELZER, KARIN DRECHSEL
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creator BARBARA NIKLAUS-HUMKE
PETRA BARTH
CHRISTEL SCHMELZER
KARIN DRECHSEL
description "formulação inalável de uma solução contendo um sal de tiotrópio". a presente invenção refere-se a uma formulação inalável de brometo de tiotrópio ou monoidrato de brometo de tiotrópio livre de propelentes dissolvida em água ou em uma mistura de água e etanol e aos aerossóis inaláveis livres de propelentes resultantes da mesma. A medicament preparation (A) contains: (a) a tiotropium salt as active agent (I), at a tiotropium concentration of 0.0005-5 wt.%; (b) water or aqueous ethanol as solvent; (c) acid to adjust the pH to 2.0-4.5; (d) a preservative; and (e) optionally (f) one or more of complexants, stabilizers, co-solvents and other auxiliaries. An independent claim is included for the production of (A), by mixing the individual components. ACTIVITY : Bronchodilator; Antiasthmatic. No biological test data provided. MECHANISM OF ACTION : Anticholinergic. No biological test data provided.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title preparação farmacêutica, sua aplicação farmacêutica, bem como processo para preparação da mesma
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