processo para produzir seletivamente monohidrato e hemipentahidrato de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico de sódio

"cristalização seletiva de sódio de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico como o monohidrato ou hemipentahidrato". a presente invenção refere-se ao monohidrato e hemipentahidrato de sódio de ácido de 3-piridil-1-hidroxietilideno-1,1-bisfosfônico, métodos de preparação do hemi...

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Hauptverfasser:	Gregory Eugene Perry, Fredrick Dana Cazer, Dennis Michael Billings, Nacy Lee Redman-Furey
Format:	Patent
Sprache:	por
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	Gregory Eugene Perry Fredrick Dana Cazer Dennis Michael Billings Nacy Lee Redman-Furey
description	"cristalização seletiva de sódio de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico como o monohidrato ou hemipentahidrato". a presente invenção refere-se ao monohidrato e hemipentahidrato de sódio de ácido de 3-piridil-1-hidroxietilideno-1,1-bisfosfônico, métodos de preparação do hemipentahidrato ou monohidrato através do controle da temperatura de nucleação e a taxa de cristalização e composições farmacêuticas contendo uma ou ambas das formas de hidratos. The present invention discloses 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium hemipentahydrate and monohydrate, methods of preparing the hemipentahydrate or monohydrate through control of the nucleation temperature and rate of crystallization and pharmaceutical compositions containing one or both of the hydrate forms.
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The present invention discloses 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium hemipentahydrate and monohydrate, methods of preparing the hemipentahydrate or monohydrate through control of the nucleation temperature and rate of crystallization and pharmaceutical compositions containing one or both of the hydrate forms.</description><language>por</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210525&DB=EPODOC&CC=BR&NR=PI0107921B8$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20210525&DB=EPODOC&CC=BR&NR=PI0107921B8$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Gregory Eugene Perry</creatorcontrib><creatorcontrib>Fredrick Dana Cazer</creatorcontrib><creatorcontrib>Dennis Michael Billings</creatorcontrib><creatorcontrib>Nacy Lee Redman-Furey</creatorcontrib><title>processo para produzir seletivamente monohidrato e hemipentahidrato de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico de sódio</title><description>"cristalização seletiva de sódio de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico como o monohidrato ou hemipentahidrato". a presente invenção refere-se ao monohidrato e hemipentahidrato de sódio de ácido de 3-piridil-1-hidroxietilideno-1,1-bisfosfônico, métodos de preparação do hemipentahidrato ou monohidrato através do controle da temperatura de nucleação e a taxa de cristalização e composições farmacêuticas contendo uma ou ambas das formas de hidratos. The present invention discloses 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium hemipentahydrate and monohydrate, methods of preparing the hemipentahydrate or monohydrate through control of the nucleation temperature and rate of crystallization and pharmaceutical compositions containing one or both of the hydrate forms.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2021</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjE0KwjAQhbtxIeodBtcGGrtQtxVFdyLuS2ymdCDNhCSKeADv4Rn0Br2YVXTv6vG-99NPbs5ziSEwOOUVdE6fruQhoMFIZ9WgjQgNW65JexUZEGpsyHVc_ZBGaO8laYZMOPKkyQgp3ilfqLsxpNGykBMpjhQqDlX7tFR-hqF9aOJh0quUCTj66iAZr1eH5Uag4wKDUyVajEW-321Tmc4WU5nPs79KLx9jTpE</recordid><startdate>20210525</startdate><enddate>20210525</enddate><creator>Gregory Eugene Perry</creator><creator>Fredrick Dana Cazer</creator><creator>Dennis Michael Billings</creator><creator>Nacy Lee Redman-Furey</creator><scope>EVB</scope></search><sort><creationdate>20210525</creationdate><title>processo para produzir seletivamente monohidrato e hemipentahidrato de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico de sódio</title><author>Gregory Eugene Perry ; Fredrick Dana Cazer ; Dennis Michael Billings ; Nacy Lee Redman-Furey</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_BRPI0107921B83</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>por</language><creationdate>2021</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>Gregory Eugene Perry</creatorcontrib><creatorcontrib>Fredrick Dana Cazer</creatorcontrib><creatorcontrib>Dennis Michael Billings</creatorcontrib><creatorcontrib>Nacy Lee Redman-Furey</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Gregory Eugene Perry</au><au>Fredrick Dana Cazer</au><au>Dennis Michael Billings</au><au>Nacy Lee Redman-Furey</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>processo para produzir seletivamente monohidrato e hemipentahidrato de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico de sódio</title><date>2021-05-25</date><risdate>2021</risdate><abstract>"cristalização seletiva de sódio de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico como o monohidrato ou hemipentahidrato". a presente invenção refere-se ao monohidrato e hemipentahidrato de sódio de ácido de 3-piridil-1-hidroxietilideno-1,1-bisfosfônico, métodos de preparação do hemipentahidrato ou monohidrato através do controle da temperatura de nucleação e a taxa de cristalização e composições farmacêuticas contendo uma ou ambas das formas de hidratos. The present invention discloses 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid sodium hemipentahydrate and monohydrate, methods of preparing the hemipentahydrate or monohydrate through control of the nucleation temperature and rate of crystallization and pharmaceutical compositions containing one or both of the hydrate forms.</abstract><oa>free_for_read</oa></addata></record>
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subjects	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	processo para produzir seletivamente monohidrato e hemipentahidrato de ácido 3-piridil-1-hidroxietilideno-1,1-bisfosfônico de sódio
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