Composto imunogenio processos para evitar a toxicose por festuca em um herbivoro para tratar a toxicose por festuca em um herbivoro anticorpo purificado lingagem de célula de hidridoma e anticorpo

An immunogenic compound comprising the formula: wherein X is selected from the group consisting of methyl and hydrogen; wherein R1 is a suitable functional group of the lysergic ring; wherein R2 is an immunogenic protein; and wherein Y is a bridge to link R1 to R2. Purified polyclonal and monoclonal...

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Hauptverfasser: FREDERICK N THOMPSON JR, JOHN A STUDEMANN, DONALD L DAWE, NICOLAS S HILL
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creator FREDERICK N THOMPSON JR
JOHN A STUDEMANN
DONALD L DAWE
NICOLAS S HILL
description An immunogenic compound comprising the formula: wherein X is selected from the group consisting of methyl and hydrogen; wherein R1 is a suitable functional group of the lysergic ring; wherein R2 is an immunogenic protein; and wherein Y is a bridge to link R1 to R2. Purified polyclonal and monoclonal antibodies specifically reactive with the immunogenic compound and reactive with the lysergic ring of ergopeptine and clavine alkaloids are described. An antibody which is an anti-idiotype of the monoclonal antibody is provided. Methods of prevention and treatment of fescue toxicosis utilizing the immunogenic compounds and antibodies of the present invention are provided.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Composto imunogenio processos para evitar a toxicose por festuca em um herbivoro para tratar a toxicose por festuca em um herbivoro anticorpo purificado lingagem de célula de hidridoma e anticorpo
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